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PD-1 抗体 (AA 21-167)

This anti-PD-1 antibody is a 小鼠 单克隆 antibody detecting PD-1 in FACS, WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN306438
发货至: 中国

Quick Overview for PD-1 抗体 (AA 21-167) (ABIN306438)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

4F12
  • 抗原表位

    • 16
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    AA 21-167

    纯化方法

    The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

    免疫原

    Recombinant human PDCD1 (21-167aa) purified from E. coli

    亚型

    IgG2b kappa
  • 应用备注

    Recommended dilution 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    PD-1

    背景

    PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PD-1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PD-1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.

    途径

    Cancer Immune Checkpoints
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