PD-1 抗体 (AA 21-167)
Our Local Distributor
北京 101111
Quick Overview for PD-1 抗体 (AA 21-167) (ABIN306438)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 21-167
-
原理
- Human PD-1 antibody
-
纯化方法
- Purified
-
免疫原
- Recombinant human PDCD1 (21-167aa) purified from E. coli
-
亚型
- IgG2b kappa
-
-
-
-
应用备注
- Recommended dilution 1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
-
-
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
-
别名
- PD-1
-
背景
- PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PD-1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PD-1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.
-
途径
- Cancer Immune Checkpoints
抗原
-