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HMOX1 抗体 (AA 12-25)

This anti-HMOX1 antibody is a 兔 多克隆 antibody detecting HMOX1 in WB, IHC 和 IHC (fro). Suitable for 人, 大鼠, 小鼠, Pig, 犬, Cow, 猴, Hamster, Bat 和 非洲爪蟾.
产品编号 ABIN305794
发货至: 中国

Quick Overview for HMOX1 抗体 (AA 12-25) (ABIN305794)

抗原

See all HMOX1 抗体
HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

适用

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人, 大鼠, 小鼠, Pig, 犬, Cow, 猴, Hamster, Bat, 非洲爪蟾

宿主

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克隆类型

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多克隆

标记

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This HMOX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 12-25

    特异性

    Recognizes human heme oxygenase-1 (HO-1), a 288 amino acid enzyme with a crucial role in heme catabolism, cleaving the heme ring to form biliverdin which is further processed to form bilirubin by a reductase enzyme. HO-1 acitivity is highest in the spleen where it is involved in the processing of senescent erythrocytes. HO-1expression can be increased during cellular stress, including heat shock. Baseline levels of expression are high in certain tissues, including spleen and liver. Enriched enzyme preparations are recommended for experimental analysis.

    无交叉反应

    预测反应

    Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Opossum, Platypus, Xenopus (100%) Turkey, Chicken, Lizard (93%).

    纯化方法

    Purified IgG

    免疫原

    Synthetic peptide with the amino acid sequence DLSEALKEATKEVHC corresponding to residues 12-25 of human heme oxygenase 1. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Opossum, Platypus, Xenopus (100%), Turkey, Chicken, Lizard (93%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: IHC, IHC-Fr, WB (1:500 - 1:2000)

    Usage: Western Blot: Heme oxygenase 1 demonstrates a single band of approximately 32kD. Immunohistology: LS-C11351 reacts with human spleen, kidney and airway biopsies, as well as pig arteries.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Short term: -20°C
    Long term: -20°C.
  • 抗原

    HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

    别名

    HMOX1 / HO-1

    背景

    Name/Gene ID: HMOX1

    Synonyms: HMOX1, BK286B10, HO-1, HSP32, Heat shock protein, 32-kD, Heme oxygenase (decycling) 1, Heme oxygenase 1, HO1

    基因ID

    3162

    途径

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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