HMOX1 抗体 (AA 12-25)
Quick Overview for HMOX1 抗体 (AA 12-25) (ABIN305794)
抗原
See all HMOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-25
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特异性
- Recognizes human heme oxygenase-1 (HO-1), a 288 amino acid enzyme with a crucial role in heme catabolism, cleaving the heme ring to form biliverdin which is further processed to form bilirubin by a reductase enzyme. HO-1 acitivity is highest in the spleen where it is involved in the processing of senescent erythrocytes. HO-1expression can be increased during cellular stress, including heat shock. Baseline levels of expression are high in certain tissues, including spleen and liver. Enriched enzyme preparations are recommended for experimental analysis.
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无交叉反应
- 犬
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预测反应
- Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Opossum, Platypus, Xenopus (100%) Turkey, Chicken, Lizard (93%).
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纯化方法
- Purified IgG
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免疫原
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Synthetic peptide with the amino acid sequence DLSEALKEATKEVHC corresponding to residues 12-25 of human heme oxygenase 1. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Opossum, Platypus, Xenopus (100%), Turkey, Chicken, Lizard (93%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: IHC, IHC-Fr, WB (1:500 - 1:2000)
Usage: Western Blot: Heme oxygenase 1 demonstrates a single band of approximately 32kD. Immunohistology: LS-C11351 reacts with human spleen, kidney and airway biopsies, as well as pig arteries. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
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别名
- HMOX1 / HO-1
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背景
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Name/Gene ID: HMOX1
Synonyms: HMOX1, BK286B10, HO-1, HSP32, Heat shock protein, 32-kD, Heme oxygenase (decycling) 1, Heme oxygenase 1, HO1 -
基因ID
- 3162
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
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