B-Cells 抗体 (FITC)
适用: 人
FACS
宿主: 小鼠
Monoclonal
FMC7
FITC
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- 抗原
- B-Cells
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes a glycoprotein antigen of 105kD expressed by B lymphocytes. The FMC7 antigen is expressed by peripheral B lymphocytes, and has been used widely in the study of B cell malignancy. FMC7 has been used extensively to differentiate various types of B cell malignancy. B-CLL is generally considered to be negative for FMC7 expression, but strong staining is seen in many other types of B cell lymphoma, including prolymphocytic leukemia and hairy cell leukemia. The nature of the FMC7 antigen has remained poorly defined following its first description in 1981. The expression pattern closely corresponds to that seen with CD22, but studies have shown that FMC7 does not recognize the CD22 Molecule itself. A recent publication by Serke et al has shown Recognizes a conformational epitope on the CD20 Molecule, most likely a multimeric complex of CD20.
- 纯化方法
- Gel filtration
- 免疫原
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HRIK cells - Human B-Lymphoblastoid line.
Type of Immunogen: Cells - 克隆位点
- FMC7
- 亚型
- IgM
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anti-B-Cells antibody (FITC)
适用: 人 FACS 宿主: 小鼠 Monoclonal FMC7 FITC
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- 应用备注
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Approved: Flo (1:1)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.1 M Tris-HCL, 0.5 mL sodium chloride, 10 mM glycine, pH 8.0, 0.09 % sodium azide, 1 % BSA.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- B-Cells
- 别名
- B Cell
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