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ZBTB7A 抗体 (N-Term)

Name: ZBTB7A 抗体 (N-Term)
SKU: ABIN3044568
Availability: OutOfStock

The 兔多克隆 anti-ZBTB7A antibody (ABIN3044568) specifically detects ZBTB7A in WB, IHC, IF, ICC 和 FACS. The antibody is reactive with 人 samples.

Western blot analysis of ZBTB7A expression in HELA whole cell lysates (lane 1). (ZBTB7A 抗体 (N-Term))

Flow Cytometry analysis of MCF-7 cells using anti-ZBTB7A antibody (ABIN3044568). (ZBTB7A 抗体 (N-Term))

FACS

ZBTB7A was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- ZBTB7A Antigen Affinity purified polyclonal antibody at 1 μg/mL. (ZBTB7A 抗体 (N-Term))

IHC (p)

Western blot analysis of ZBTB7A using anti-ZBTB7A antibody (ABIN3044568). (ZBTB7A 抗体 (N-Term))

IHC analysis of ZBTB7A using anti-ZBTB7A antibody (ABIN3044568). (ZBTB7A 抗体 (N-Term))

IHC

IF analysis of ZBTB7A using anti-ZBTB7A antibody (ABIN3044568). (ZBTB7A 抗体 (N-Term))

IHC

6 images

产品编号 ABIN3044568

发货至: 中国

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Quick Overview for ZBTB7A 抗体 (N-Term) (ABIN3044568)

抗原

See all ZBTB7A 抗体

ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

适用

人

宿主

兔

克隆类型

多克隆

标记

This ZBTB7A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Discover our top product ZBTB7A Primary Antibody

抗原表位
15

8

7

6

2

1

1

1

1

1

1

1

1

1

1
N-Term

原理

Anti-ZBTB7A Antibody

序列

DLLDRQILAA DAGADAGQLD LVDQIDQRNL LRAKEYLEF

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins.

预测反应

different from the related mouse sequence by eleven amino acids,and from the related rat sequence by ten amino acids.

产品特性

Anti-ZBTB7A Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human ZBTB7A, different from the related mouse sequence by eleven amino acids, and from the related rat sequence by ten amino acids.

亚型

IgG
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 151-250) antibody
ZBTB7A 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (N-Term) antibody
ZBTB7A 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) antibody
ZBTB7A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 1-108) antibody
ZBTB7A 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2A2 unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (N-Term) antibody
ZBTB7A 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) antibody
ZBTB7A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2395 unconjugated Recombinant Antibody

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (C-Term) antibody
ZBTB7A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (N-Term) antibody
ZBTB7A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 224-273) antibody
ZBTB7A 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 114-163) antibody
ZBTB7A 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

别名

ZBTB7A

背景

Background: Zinc finger and BTB domain-containing protein 7A is a protein that in humans is encoded by the ZBTB7A gene. ZBTB7A has a critical oncosuppressive role in the prostate. Prostate-specific inactivation of ZBTB7A leads to a marked acceleration of PTEN loss-driven prostate tumorigenesis through bypass of PTEN loss-induced cellular senescence. It has been showed that ZBTB7A physically interacts with SOX9 and functionally antagonizes its transcriptional activity on key target genes such as MIA, which is involved in tumor cell invasion, and H19, a long noncoding RNA precursor for an RB-targeting microRNA. Inactivation of ZBTB7A in vivo leads to RB downregulation, bypass of PTEN loss-induced cellular senescence, and invasive prostate cancer. Notably, it has been also found that ZBTB7A is genetically lost, as well as downregulated at both the mRNA and protein levels, in a subset of human advanced prostate cancers. Therefore, ZBTB7A is identified as a context-dependent cancer gene that can act as an oncogene in some contexts but that also has oncosuppressive-like activity in PTEN-null tumors.
Gene Full Name: zinc finger and BTB domain containing 7A

分子量

72 kDa

基因ID

51341

UniProt

O95365