VRK1 抗体 (C-Term)
Quick Overview for VRK1 抗体 (C-Term) (ABIN3044560)
抗原
See all VRK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 292-329, C-Term
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原理
- Anti-VRK1 Antibody Picoband®
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序列
- EKNKPGEIAK YMETVKLLDY TEKPLYENLR DILLQGLK
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-VRK1 Antibody Picoband® (ABIN3044560). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human VRK1, different from the related mouse sequence by three amino acids.
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亚型
- IgG
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anti-Vaccinia Related Kinase 1 (VRK1) (AA 287-396) antibody
VRK1 适用: 人 WB, ELISA, IP, IF, RNAi 宿主: 小鼠 Monoclonal 4F9 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (N-Term) antibodyVRK1 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 5D1 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 257-396) antibodyVRK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 1-396) antibodyVRK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 1-396) antibodyVRK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人 WB 宿主: 小鼠 Monoclonal 5C1 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 287-396) antibodyVRK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (Internal Region) antibodyVRK1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: VRK1 vaccinia related kinase 1". 2. Nezu J, Oku A, Jones MH, Shimane M (Feb 1998). "Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase". Genomics 45 (2): 327-31. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- VRK1 (Vaccinia Related Kinase 1 (VRK1))
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别名
- VRK1
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背景
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Synonyms: Serine/threonine-protein kinase VRK1,2.7.11.1,Vaccinia-related kinase 1,VRK1,
Tissue Specificity: Widely expressed. Highly expressed in fetal liver, testis and thymus. .
Background: Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
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分子量
- 55 kDa
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基因ID
- 7443
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UniProt
- Q99986
抗原
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