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VRK1 抗体 (C-Term)

VRK1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044560
发货至: 中国
  • 抗原 See all VRK1 抗体
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    抗原表位
    • 14
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 292-329, C-Term
    适用
    • 44
    • 11
    • 3
    人, 大鼠
    宿主
    • 38
    • 6
    克隆类型
    • 40
    • 4
    多克隆
    标记
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VRK1 antibody is un-conjugated
    应用范围
    • 36
    • 15
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    原理
    Anti-VRK1 Antibody Picoband®
    序列
    EKNKPGEIAK YMETVKLLDY TEKPLYENLR DILLQGLK
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-VRK1 Antibody Picoband® (ABIN3044560). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human VRK1, different from the related mouse sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product VRK1 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. "Entrez Gene: VRK1 vaccinia related kinase 1". 2. Nezu J, Oku A, Jones MH, Shimane M (Feb 1998). "Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase". Genomics 45 (2): 327-31.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    别名
    VRK1 (VRK1 产品)
    背景

    Synonyms: Serine/threonine-protein kinase VRK1,2.7.11.1,Vaccinia-related kinase 1,VRK1,

    Tissue Specificity: Widely expressed. Highly expressed in fetal liver, testis and thymus. .

    Background: Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    分子量
    55 kDa
    基因ID
    7443
    UniProt
    Q99986
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