VEGFD 抗体 (AA 89-205)
(1 reference)Quick Overview for VEGFD 抗体 (AA 89-205) (ABIN3044524)
抗原
See all VEGFD (Figf) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 89-205
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原理
- Anti-VEGFD/FIGF Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-VEGFD/FIGF Antibody Picoband® (ABIN3044524). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human VEGFD recombinant protein (Position: F89-R205). Human VEGFD shares 94% and 94.9% amino acid (aa) sequence identity with mouse and rat VEGFD, respectively.
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亚型
- IgG
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anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 89-354) antibody
Figf 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 20-220) antibodyFigf 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) antibodyFigf 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 1-354) antibodyFigf 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 322-352) antibodyFigf 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 93-201) antibodyFigf 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2-2# unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 98-206) antibodyFigf 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 89-205) antibodyFigf 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 1-354) antibodyFigf 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) antibody (HRP)Figf 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
1. Achen, M. G., Jeltsch, M., Kukk, E., Makinen, T., Vitali, A., Wilks, A. F., Alitalo, K., Stacker, S. A. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc. Nat. Acad. Sci. 95: 548-553, 1998. 2. Stacker, S. A., Caesar, C., Baldwin, M. E., Thornton, G. E., Williams, R. A., Prevo, R., Jackson, D. G., Nishikawa, S., Kubo, H., Achen, M. G. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nature Med. 7: 186-191, 2001. 3. Yamada, Y., Nezu, J., Shimane, M., Hirata, Y. Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. Genomics 42: 483-488, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein." in: International journal of oncology, Vol. 49, Issue 1, pp. 123-32, (2017) (PubMed).
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: "VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein." in: International journal of oncology, Vol. 49, Issue 1, pp. 123-32, (2017) (PubMed).
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- VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
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别名
- VEGFD
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背景
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Synonyms: Vascular endothelial growth factor D,VEGF-D,c-Fos-induced growth factor,FIGF,FIGF,VEGFD,
Tissue Specificity: Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
Background: C-fos induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al. (1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al. (1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al. (2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.
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分子量
- 40 kDa
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基因ID
- 2277
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UniProt
- O43915
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途径
- RTK signaling
抗原
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