APOA1 抗体 (AA 25-259)
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北京 101111
Quick Overview for APOA1 抗体 (AA 25-259) (ABIN3044502)
抗原
See all APOA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-259
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原理
- Anti-Apolipoprotein A I/APOA1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Apolipoprotein A I/APOA1 Antibody (ABIN3044502). Tested in IHC, WB applications. This antibody reacts with Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat APOA1 recombinant protein (Position: D25-A259). Rat APOA1 shares 61.7% and 68.6% amino acid (aa) sequence identity with human and mouse APOA1, respectively.
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亚型
- IgG
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anti-Apolipoprotein A-I (APOA1) antibody
APOA1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-264) antibodyAPOA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-265) antibodyAPOA1 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 10-37) antibodyAPOA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 51-150) antibodyAPOA1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 20-267) antibodyAPOA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat
Western blot, 0.1-0.5 μg/mL, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- Apoa1
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背景
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Synonyms: Apolipoprotein A-I,Apo-AI,ApoA-I,Apolipoprotein A1,Proapolipoprotein A-I,ProapoA-I,Apoa1,
Tissue Specificity: Major protein of plasma HDL, also found in chylomicrons.
Background: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.
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分子量
- 24 kDa
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基因ID
- 25081
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UniProt
- P04639
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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