PPP2CA 抗体 (N-Term)
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北京 101111
Quick Overview for PPP2CA 抗体 (N-Term) (ABIN3044492)
抗原
See all PPP2CA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-PP2A-alpha/PPP2CA Antibody
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序列
- FTKELDQWIE QLNEC
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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产品特性
- Anti-PP2A-alpha/PPP2CA Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A-alpha, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (C-Term) antibody
PPP2CA 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309) antibodyPPP2CA 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309) antibodyPPP2CA 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309), (Catalytic Subunit) antibodyPPP2CA 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (pTyr307) antibodyKD Validated PPP2CA 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2300 unconjugated Recombinant Antibody
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (Thr278) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 274-304), (C-Term) antibodyPPP2CA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB6000 unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) antibodyPPP2CA 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal P6C7 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Sphingomyelinase-induced ceramide production stimulate calcium-independent JNK and PP2A activation following cerebral ischemia." in: Brain injury, Vol. 23, Issue 13-14, pp. 1073-80, (2009) (PubMed).
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- PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
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别名
- PPP2CA
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背景
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Background: The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide.It is localized to chromosome 5. The gene (approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of protein serine/threonine phosphatase 2A catalytic subunit (PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
Gene Full Name: protein phosphatase 2 catalytic subunit alpha
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分子量
- 36 kDa
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基因ID
- 5515
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UniProt
- P67775
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途径
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
抗原
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