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PPP2CA 抗体 (AA 1-309)

PPP2CA 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043356
发货至: 中国
  • 抗原 See all PPP2CA 抗体
    PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
    抗原表位
    • 16
    • 14
    • 13
    • 8
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-309
    适用
    • 67
    • 56
    • 46
    • 13
    • 10
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 75
    • 8
    • 4
    • 2
    • 1
    克隆类型
    • 75
    • 15
    多克隆
    标记
    • 56
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP2CA antibody is un-conjugated
    应用范围
    • 75
    • 30
    • 18
    • 17
    • 15
    • 14
    • 13
    • 13
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PPP2CA) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    PP2A-alpha shares 100 % cross reactivity with PPP2CB.
    产品特性
    Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PPP2CA) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: protein phosphatase 2, catalytic subunit, alpha isozyme
    Protein Name: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PP2A-alpha recombinant protein (Position: M1-L309). Human PP2A-alpha shares 100% amino acid (aa) sequence identity with both mouse and rat PP2A-alpha.
    亚型
    IgG
    Top Product
    Discover our top product PPP2CA Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for PP2A-alpha is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
    别名
    PPP2CA (PPP2CA 产品)
    别名
    PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, RP-C antibody, PP2A antibody, R75353 antibody, Pp2a1 antibody, pp2ac antibody, zgc:110641 antibody, protein phosphatase 2 catalytic subunit alpha antibody, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antibody, protein phosphatase 2, catalytic subunit, alpha isozyme antibody, protein phosphatase 2 catalytic subunit alpha L homeolog antibody, protein phosphatase 2, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody, PPP2CA antibody, Ppp2ca antibody, ppp2ca.L antibody, ppp2cb antibody, LOC471633 antibody, ppp2ca antibody
    背景
    The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is localized to chromosome 5. The gene (approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of protein serine/threonine phosphatase 2A catalytic subunit (PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.

    Synonyms: PP2A alpha antibody|PP2A-alpha antibody|PP2AA_HUMAN antibody|PP2Aalpha antibody|PP2Ac antibody|PP2CA antibody|PP2Calpha antibody|PPP2CA antibody|Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform antibody|Protein phosphatase 2 catalytic subunit alpha isoform antibody|Protein phosphatase 2, catalytic subunit, alpha isozyme antibody|Protein phosphatase 2A catalytic subunit, alpha isoform antibody|Replication protein C antibody|RP C antibody|RP-C antibody|RPC antibody|Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody|Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody
    基因ID
    5515
    UniProt
    P67775
    途径
    PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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