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Decorin 抗体 (C-Term)

Name: Decorin 抗体 (C-Term)
SKU: ABIN3044362
Availability: OutOfStock

This anti-Decorin antibody is a 兔多克隆 antibody detecting Decorin in WB. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 2+ publications.

Anti-Decorin antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Kidney Tissue Lysate Lane 3: SMMC Cell Lysate (Decorin 抗体 (C-Term))

Anti-Decorin antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Lung Tissue Lysate Lane 3: Rat Spleen Tissue Lysate Lane 4: SMMC Cell Lysate Lane 5: SMMC Cell Lysate (Decorin 抗体 (C-Term))

3 images

(2 references)

产品编号 ABIN3044362

发货至: 中国

Quick Overview for Decorin 抗体 (C-Term) (ABIN3044362)

抗原

See all Decorin (DCN) 抗体

Decorin (DCN)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Decorin antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product DCN Primary Antibody

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AA 343-359, C-Term

原理

Anti-Decorin/DCN Antibody Picoband®

序列

TFRCVYVRSA IQLGNYK

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Decorin/DCN Antibody (ABIN3044362). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Decorin, identical to the related mouse sequence, and different from the related rat sequence by three amino acids.

亚型

IgG
anti-Decorin (DCN) (AA 31-359) antibody
DCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Decorin (DCN) (AA 1-359) antibody
DCN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H4-1F4 unconjugated

anti-Decorin (DCN) (AA 263-324) antibody
DCN 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5E8E7 unconjugated

anti-Decorin (DCN) (Internal Region) antibody
DCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Decorin (DCN) antibody
DCN 适用: 人 WB, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Decorin (DCN) (AA 31-359) antibody
DCN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Decorin (DCN) (AA 122-150) antibody
DCN 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19595 unconjugated

anti-Decorin (DCN) (AA 31-359) antibody
DCN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Decorin (DCN) (AA 212-336) antibody
DCN 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DCN-3523 unconjugated

anti-Decorin (DCN) antibody
DCN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Danielson, K. G., Fazzio, A., Cohen, I., Cannizzaro, L. A., Eichstetter, I., Iozzo, R. V. : The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5-prime untranslated region, and mapping of the gene to chromosome 12q23. Genomics 15: 146-160, 1993. 2. Vetter, U., Vogel, W., Just, W., Young, M. F., Fisher, L. W. : Human decorin gene: intron-exon junctions and chromosomal localization. Genomics 15: 161-168, 1993. 3. Scholzen, T., Solursh, M., Suzuki, S., Reiter, R., Morgan, J. L., Buchberg, A. M., Siracusa, L. D., Iozzo, R. V. : The murine decorin: complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation. J. Biol. Chem. 269: 28270-28281, 1994.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Han, Wang, Jiang, Ma, Tian, Zang, Ma: "An Animal Model of Modic Changes by Embedding Autogenous Nucleus Pulposus inside Subchondral Bone of Lumbar Vertebrae." in: Scientific reports, Vol. 6, pp. 35102, (2016) (PubMed).

Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).
抗原

Decorin (DCN)

别名

DCN

背景

Synonyms: Decorin,Bone proteoglycan II,PG-S2,PG40,DCN,SLRR1B,
Tissue Specificity: Ubiquitously expressed. .
Background: Decorin is a proteoglycan on average 90-140 kilodaltons (kD) in size. The human decorin gene spans more than 38 kb and contains 8 exons and very large introns, 2 of which are 5.4 and more than 13.2 kb. And the human decorin gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are though to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for the decorin gene. Mutations in the decorin gene are associated with congenital stromal corneal dystrophy.
Sequence Similarities: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.

分子量

40-50 kDa, 80-140 kDa

UniProt

P07585

途径

Glycosaminoglycan Metabolic Process