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- 抗原 See all FGF8 抗体
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
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抗原表位
- AA 163-185, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGF8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Fibroblast growth factor 8(FGF8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- FMKRLPRGHH TTEQSLRFEF LNY
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Fibroblast growth factor 8(FGF8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: fibroblast growth factor 8(androgen-induced)
Protein Name: Fibroblast growth factor 8(FGF-8) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human FGF8(163-185aa FMKRLPRGHHTTEQSLRFEFLNY), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product FGF8 Primary Antibody
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anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibody
FGF8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 131-233) antibodyFGF8 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) antibodyFGF8 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 30-59), (N-Term) antibodyFGF8 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40263 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibodyFGF8 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Internal Region) antibodyFGF8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 23-143) antibodyFGF8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Internal Region) antibodyFGF8 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 32-66), (N-Term) antibodyFGF8 适用: 人 WB 宿主: 兔 Polyclonal RB49207 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibodyFGF8 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2A12 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
- 别名
- FGF8 (FGF8 产品)
- 别名
- Aigf antibody, Fgf-8 antibody, AIGF antibody, FGF-8 antibody, HBGF-8 antibody, HH6 antibody, KAL6 antibody, fibroblast growth factor 8 antibody, Fgf8 antibody, FGF8 antibody
- 背景
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Fibroblast growth factor 8(androgen-induced), also known as FGF8 or AIGF, is a human gene which maps to 10q24. The protein encoded by this gene are secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation, regionalization of the brain, and organogenesis of the limb and face as an embryonic epithelial factor. The adult expression of FGF8 is restricted to gonads, including testes and ovaries. FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner. It also may play an important role in growth and patterning of limbs, face, and central nervous system. FGF8 is expressed in increased levels in breast cancer and in lactating human breast, it was also detected in human milk. A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, ovary, fallopian tube, and uterus.
Synonyms: AIGF antibody|Androgen induced growth factor antibody|Androgen-induced growth factor antibody|FGF 8 antibody|FGF-8 antibody|FGF8 antibody|FGF8_HUMAN antibody|Fibroblast growth factor 8(androgen induced) antibody|Fibroblast growth factor 8 antibody|Fibroblast growth factor 8 precursor antibody|HBGF 8 antibody|HBGF-8 antibody|HBGF8 antibody|Heparin-binding growth factor 8 antibody - UniProt
- P55075
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
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