Apoptosis Inhibitor 5 抗体 (C-Term)
Quick Overview for Apoptosis Inhibitor 5 抗体 (C-Term) (ABIN3044316)
抗原
See all Apoptosis Inhibitor 5 (API5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 487-504, C-Term
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原理
- Anti-Apoptosis inhibitor 5/API5 Antibody Picoband®
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序列
- KYSSNLGNFN YERSLQGK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Apoptosis inhibitor 5/API5 Antibody (ABIN3044316). Tested in IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Apoptosis inhibitor 5, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Apoptosis Inhibitor 5 (API5) (AA 400-504) antibody
API5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Apoptosis Inhibitor 5 (API5) antibodyAPI5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (C-Term) antibodyAPI5 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (C-Term) antibodyAPI5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (AA 2-360) antibodyAPI5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (AA 396-524) antibodyAPI5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (C-Term) antibodyAPI5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (AA 351-460) antibodyAPI5 适用: 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) antibodyAPI5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Inhibitor 5 (API5) (AA 421-470) antibodyAPI5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human, Mouse
Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Hartz, P. A.Personal Communication.Baltimore, Md. 12/12/2005. 2. Tewari, M., Yu, M., Ross, B., Dean, C., Giordano, A., Rubin, R. : AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Cancer Res. 57: 4063-4069, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Apoptosis Inhibitor 5 (API5)
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别名
- API5
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背景
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Synonyms: Apoptosis inhibitor 5,API-5,Antiapoptosis clone 11 protein,AAC-11,Cell migration-inducing gene 8 protein,Fibroblast growth factor 2-interacting factor,FIF,Protein XAGL,API5,MIG8,
Tissue Specificity: Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer. .
Background: Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death (apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.
Sequence Similarities: Belongs to the API5 family.
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分子量
- 59 kDa
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途径
- Growth Factor Binding
抗原
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