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Annexin V 抗体 (Middle Region)

Name: Annexin V 抗体 (Middle Region)
SKU: ABIN3044315
Availability: OutOfStock

ANXA5 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

Anti-Annexin V antibody, Western blotting All lanes: Anti Annexin V at 0. (Annexin V 抗体 (Middle Region))

Anti-Annexin V antibody, IHC(P) IHC(P): Rat Liver Tissue (Annexin V 抗体 (Middle Region))

IHC

Anti-Annexin V antibody, ICC ICC: HCT116 Cell (Annexin V 抗体 (Middle Region))

IHC

Anti-Annexin V antibody, ICC ICC: HELA Cell (Annexin V 抗体 (Middle Region))

IHC

5 images

(7 references)

产品编号 ABIN3044315

发货至: 中国

Datasheet as PDF

抗原 See all Annexin V (ANXA5) 抗体

Annexin V (ANXA5) (Annexin A5 (ANXA5))
抗原表位
19

8

7

7

7

4

4

3

2

2

2

1

1

1

1

1

1

1

1
AA 88-102, Middle Region
适用
113

58

42

10

5

5

5

4

4

4

3

3

3

2

2

2

1
人, 小鼠, 大鼠
宿主
115

24
兔
Compatible Secondaries
克隆类型
107

30
多克隆
标记
67

18

16

4

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This Annexin V antibody is un-conjugated
应用范围
92

40

36

20

20

19

16

13

11

5

4

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

原理

Anti-Annexin V/ANXA5 Antibody Picoband®

序列

SRLYDAYELK HALKG

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Annexin V/ANXA5 Antibody (ABIN3044315). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human Annexin V, identical to the related rat and mouse sequences.

亚型

IgG

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anti-Annexin A5 (ANXA5) (AA 160-320) antibody
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anti-Annexin A5 (ANXA5) (AA 1-320) antibody
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anti-Annexin A5 (ANXA5) (AA 160-320) antibody
ANXA5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B9F3 unconjugated

anti-Annexin A5 (ANXA5) (AA 2-320) antibody
ANXA5 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) (AA 88-102) antibody
ANXA5 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) (AA 2-320) antibody
ANXA5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Annexin A5 (ANXA5) antibody
ANXA5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunocytochemistry , 0.5-1 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Kaplan, R., Jaye, M., Burgess, W. H., Schlaepfer, D. D., Haigler, H. T. : Cloning and expression of cDNA for human endonexin II, a Ca(2+) and phospholipid binding protein. J. Biol. Chem. 263 2. Rodriguez-Garcia, M. I., Kozak, C. A., Morgan, R. O., Fernandez, M. P. : Mouse annexin V chromosomal localization, cDNA sequence conservation, and molecular evolution. Genomics 31: 151-157, 1996. 3. Grundmann, U., Abel, K.-J., Bohn, H., Lobermann, H., Lottspeich, F., Kupper, H. : Characterization of cDNA encoding human placental anticoagulant protein (PP4): homology with the lipocortin family. Proc. Nat. Acad. Sci. 85: 3708-3712, 1988.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Manville, Abbott: "Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket." in: Nature communications, Vol. 9, Issue 1, pp. 3845, (2018) (PubMed).

Sun, Kang, Yao, Chen, Sun, An, Jiang, Wang, Hu: "Dehydrocostus lactone suppressed the proliferation, migration, and invasion of colorectal carcinoma through the downregulation of eIF4E expression." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 641-8, (2015) (PubMed).

Ji, Li, Wei, Kong, Jin, Chen, Li, Deng: "Effect of celastrol on growth inhibition of prostate cancer cells through the regulation of hERG channel in vitro." in: BioMed research international, Vol. 2015, pp. 308475, (2015) (PubMed).

Xu, Bi, Li, Fang, Zhou, Li, Chi, Wan, Shen: "Morphological and proteomic analyses reveal that unsaturated guluronate oligosaccharide modulates multiple functional pathways in murine macrophage RAW264.7 cells." in: Marine drugs, Vol. 13, Issue 4, pp. 1798-818, (2015) (PubMed).

Hu, Dong, Shi, Deng, Li, Lu: "Evaluation of a novel tetra-functional branched poly(ethylene glycol) crosslinker for manufacture of crosslinked, decellularized, porcine aortic valve leaflets." in: Journal of biomedical materials research. Part B, Applied biomaterials, Vol. 102, Issue 2, pp. 322-36, (2014) (PubMed).

Xiong, Ma, Zhang, Shao, Zhang, Zhou: "Apoptosis induced by ?,?-dimethylacrylshikonin is associated with Bcl-2 and NF-?B in human breast carcinoma MCF-7 cells." in: Oncology letters, Vol. 6, Issue 6, pp. 1789-1793, (2013) (PubMed).

Jin, Liu, Wang, Xu, Yang, Lu, Sun, Hu: "Protective effects of [Gly14]-Humanin on beta-amyloid-induced PC12 cell death by preventing mitochondrial dysfunction." in: Neurochemistry international, Vol. 56, Issue 3, pp. 417-23, (2010) (PubMed).
抗原

Annexin V (ANXA5) (Annexin A5 (ANXA5))

别名

ANXA5 (ANXA5 产品)

背景

Synonyms: Annexin A5,Anchorin CII,Annexin V,Annexin-5,Calphobindin I,CBP-I,Endonexin II,Lipocortin V,Placental anticoagulant protein 4,PP4,Placental anticoagulant protein I,PAP-I,Thromboplastin inhibitor,Vascular anticoagulant-alpha,VAC-alpha,ANXA5,ANX5, ENX2, PP4,
Background: Annexin V also know as endonnexin II (ENX2),or placental protein 4 (PP4). Endonexin II is a member of the family of Ca (2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. It has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2 (basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The PP4 cDNA encoded a protein of 320 amino acid residues. A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. PP4 is an anticoagulant protein that acts as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Sequence Similarities: Belongs to the annexin family.

分子量

36 kDa

UniProt

P08758

途径

Apoptosis