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FGF1 抗体 (AA 16-155)

This anti-FGF1 antibody is a 兔 多克隆 antibody detecting FGF1 in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN3044308
发货至: 中国

Quick Overview for FGF1 抗体 (AA 16-155) (ABIN3044308)

抗原

See all FGF1 抗体
FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FGF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 16-155

    原理

    Anti-Fibroblast growth factor 1 FGF1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Fibroblast growth factor 1 FGF1 Antibody (ABIN3044308). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human FGF1 recombinant protein (Position: F16-D155).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free or No BSA in your order note.

    储存液

    Sodium azide, Without preservative

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Zhang, Wang, Wang, Jiang, Yu, Chong, Fu: "Ferulic acid ameliorates nerve injury induced by cerebral ischemia in rats." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 972-976, (2015) (PubMed).

    Zhou, Ren, Zhu, Yan, Wang, Song, Li, Ouyang, Pang: "Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells." in: Molecular and cellular biochemistry, Vol. 354, Issue 1-2, pp. 39-46, (2011) (PubMed).

    Gu, Zhang, Wu, Xu, Cui, Yang, Zhao, Sun: "Differential expression of decorin, EGFR and cyclin D1 during mammary gland carcinogenesis in TA2 mice with spontaneous breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 6, (2010) (PubMed).

  • 抗原

    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

    别名

    FGF1

    背景

    Synonyms: Fibroblast growth factor 1,FGF-1,Acidic fibroblast growth factor,aFGF,Endothelial cell growth factor,ECGF,Heparin-binding growth factor 1,HBGF-1,FGF1,FGFA,

    Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .

    Background: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. Human FGF1 shares 96 % amino acid sequence homology with both rat and mouse. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is though to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.

    Sequence Similarities: Belongs to the heparin-binding growth factors family.

    分子量

    26 kDa

    UniProt

    P05230

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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