HTR2A 抗体 (C-Term)
Quick Overview for HTR2A 抗体 (C-Term) (ABIN3044288)
抗原
See all HTR2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 418-432, C-Term
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原理
- Anti-5HT2A Receptor/HTR2A Antibody Picoband®
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序列
- AYKSSQLQMG QKKNS
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-5HT2A Receptor/HTR2A Antibody (ABIN3044288). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2A Receptor, different from the mouse sequence by one amino acid.
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亚型
- IgG
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anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 65-160) antibody
HTR2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 51-150) antibodyHTR2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 296-309) antibodyVerified HTR2A 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 385-471) antibodyHTR2A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, Pig, Bat, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 40-52), (Extracellular) antibodyHTR2A 适用: 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 16-30), (N-Term) antibodyHTR2A 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52772 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 21-120) antibodyHTR2A 适用: 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 171-270) antibodyHTR2A 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, 小鼠, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Cook EH, Fletcher KE, Wainwright M, Marks N, Yan SY, Leventhal BL (August 1994). "Primary structure of the human platelet serotonin 5-HT2 receptor: identity with frontal cortex serotonin 5-HT2A receptor". J. Neurochem. 63 (2): 465-9. 2. Elphick GF, Querbes W, Jordan JA, Gee GV, Eash S, Manley K, Dugan A, Stanifer M, Bhatnagar A, Kroeze WK, Roth BL, Atwood WJ (2004). "The human polyomavirus, JCV, uses serotonin receptors to infect cells". Science 306 (5700): 1380-3. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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别名
- HTR2A
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背景
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Synonyms: 5-hydroxytryptamine receptor 2A,5-HT-2,5-HT-2A,Serotonin receptor 2A,HTR2A,HTR2,
Tissue Specificity: Detected in brain cortex (at protein level). Detected in blood platelets. .
Background: The mammalian HTR2A (5-HT2A receptor) is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbit frontal cortex. This receptor was given importance first as the target of psychedelic drugs like LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones.5-HT2A also happens to be a necessary receptor for the spread of the human polyoma virus called JC virus. Sparkes et al. (1991) concluded that the gene is located on 13q14-q21 in man and on chromosome 14 in the mouse.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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分子量
- 50 kDa
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UniProt
- P28223
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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