MCM3 抗体 (N-Term)
Quick Overview for MCM3 抗体 (N-Term) (ABIN3044243)
抗原
See all MCM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-27, N-Term
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原理
- Anti-MCM3 Antibody
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序列
- REAQRDYLDF LDDEE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MCM3 Antibody (ABIN3044243). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MCM3, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibody
MCM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-503M unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (C-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠, 马, Pig, Cow, 豚鼠, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (N-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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别名
- MCM3
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背景
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Synonyms: DNA replication licensing factor MCM3,3.6.4.12,DNA polymerase alpha holoenzyme-associated protein P1,P1-MCM3,RLF subunit beta,p102,MCM3,
Tissue Specificity: Heart, liver, duodenum, blood vessels and kidney.
Background: MCM3 (MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 3), also called RLFB or P1 PROTEIN, is a protein that in humans is encoded by the MCM3 gene. MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The MCM3 gene is mapped to 6p12.2. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact ly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Sequence Similarities: Belongs to the MCM family.
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分子量
- 100-110 kDa
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UniProt
- P25205
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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