ABCC1 抗体 (C-Term)
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北京 101111
Quick Overview for ABCC1 抗体 (C-Term) (ABIN3044230)
抗原
See all ABCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1514-1531, C-Term
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原理
- Anti-MRP1/ABCC1 Antibody
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序列
- LLQQRGLFYS MAKDAGLV
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MRP1/ABCC1 Antibody (ABIN3044230). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MRP1, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) (AA 1219-1469) antibody
ABCC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) antibodyABCC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) (N-Term) antibodyABCC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) antibodyKD Validated ABCC1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2970 unconjugated Recombinant Antibody
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) (AA 850-960) antibodyABCC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) antibodyABCC1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) antibodyABCC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) (Internal Region) antibodyVerified ABCC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) (AA 816-915) antibodyABCC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) antibodyABCC1 适用: 人 WB, FACS, ELISA, Coat 宿主: 小鼠 Monoclonal MRP1-1343 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Acetazolamide Suppresses Multi-Drug Resistance-Related Protein 1 and P-Glycoprotein Expression by Inhibiting Aquaporins Expression in a Mesial Temporal Epilepsy Rat Model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 5818-5825, (2018) (PubMed).
: "Characteristics of doxorubicin-selected multidrug-resistant human leukemia HL-60 cells with tolerance to arsenic trioxide and contribution of leukemia stem cells." in: Oncology letters, Vol. 15, Issue 1, pp. 1255-1262, (2018) (PubMed).
: "Enhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomes." in: International journal of nanomedicine, Vol. 10, pp. 6615-32, (2016) (PubMed).
: "Enhanced autophagy reveals vulnerability of P-gp mediated epirubicin resistance in triple negative breast cancer cells." in: Apoptosis : an international journal on programmed cell death, Vol. 21, Issue 4, pp. 473-88, (2016) (PubMed).
: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
: "The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats." in: Environmental toxicology and pharmacology, Vol. 35, Issue 1, pp. 109-16, (2013) (PubMed).
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: "Acetazolamide Suppresses Multi-Drug Resistance-Related Protein 1 and P-Glycoprotein Expression by Inhibiting Aquaporins Expression in a Mesial Temporal Epilepsy Rat Model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 5818-5825, (2018) (PubMed).
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- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
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别名
- ABCC1
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背景
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Synonyms: Multidrug resistance-associated protein 1,ATP-binding cassette sub-family C member 1,Leukotriene C (4) transporter,LTC4 transporter,ABCC1,MRP, MRP1,
Tissue Specificity: Lung, testis and peripheral blood mononuclear cells.
Background: Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
Sequence Similarities: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
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分子量
- 29 kDa
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UniProt
- P33527
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途径
- SARS-CoV-2 Protein Interactome
抗原
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