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Haptoglobin 抗体 (Middle Region)

Name: Haptoglobin 抗体 (Middle Region)
SKU: ABIN3044209
Availability: OutOfStock

HP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

Anti-Haptoglobin antibody, Western blotting Lane 1:RAJI Cell Lysate Lane 2:HL-60 Cell Lysate Lane 3:HUT102 Cell Lysate Lane 4:JURKAT Cell Lysate Lane 5:CEM Cell Lysate (Haptoglobin 抗体 (Middle Region))

Anti-Haptoglobin antibody, IHC(P) IHC(P): Human Lung Cancer Tissue (Haptoglobin 抗体 (Middle Region))

IHC

2 images

(1 reference)

产品编号 ABIN3044209

发货至: 中国

Datasheet as PDF

抗原 See all Haptoglobin (HP) 抗体

Haptoglobin (HP)
抗原表位
14

7

6

5

4

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 294-309, Middle Region
适用
87

42

39

6

4

3

1

1

1

1

1
人
宿主
86

13

8

5

3

2
兔
Compatible Secondaries
克隆类型
97

19
多克隆
标记
58

13

10

5

4

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Haptoglobin antibody is un-conjugated
应用范围
80

48

35

20

19

15

12

12

11

7

6

5

4

3

3

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Haptoglobin/HP Antibody Picoband®

序列

DHLKYVMLPV ADQDQC

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Rabbit IgG polyclonal antibody for Haptoglobin(HP) detection. Tested with WB, IHC-P in Human.
Gene Name: haptoglobin
Protein Name: Haptoglobin

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human Haptoglobin.

亚型

IgG

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HP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated

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HP 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB28443 unconjugated

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HP 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

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anti-Haptoglobin (HP) antibody
HP 适用: 人 IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Asakawa, J., Kodaira, M., Nakamura, N., Satoh, C., Fujita, M. Chimerism in humans after intragenic recombination at the haptoglobin locus during early embryogenesis. Proc. Nat. Acad. Sci. 96: 10314-10319, 1999. 2. Bensi, G., Raugei, G., Klefenz, H., Cortese, R. Structure and expression of the human haptoglobin locus. EMBO J. 4: 119-126, 1985. 3. Bloom, G. E., Gerald, P. S., Reisman, L. E. Ring D chromosome: a second case associated with anomalous haptoglobin inheritance. Science 156: 1746-1748, 1967.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Cao, Chen, Gao, Hu, Liang, Xiao: "Identification of a protein associated with the activity of cytokine-induced killer cells." in: Oncology letters, Vol. 14, Issue 6, pp. 6937-6942, (2017) (PubMed).
抗原

Haptoglobin (HP)

别名

HP (HP 产品)

背景

Synonyms: Haptoglobin,Zonulin,Haptoglobin alpha chain,Haptoglobin beta chain,HP,
Tissue Specificity: Expressed by the liver and secreted in plasma.
Background: Haptoglobin (HP), is a protein that in humans is encoded by the HP gene. Haptoglobin, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha and 2 beta polypeptides that are covalently associated by disulfide bonds. Haptoglobin is homologous to serine proteases of the chymotrypsinogen family. In the chimpanzee, there are 3 genes in the haptoglobin family (haptoglobin, HP, haptoglobin-related, HPR, and haptoglobin-primate, HPP), whereas only 2 genes exist in humans (HP and HPR). There are similarities between the primary structures of the alpha chain and of light chains of gamma globulins. The alpha haptoglobin locus is on the long arm of chromosome 16, where its exact cytogenetic location is 16q22.2. A major function of haptoglobin is to bind hemoglobin (Hb) to form a stable Hp-Hb complex and thereby prevent Hb-induced oxidative tissue damage. Haptoglobin is an unusual secretory protein in that it is proteolytically processed in the endoplasmic reticulum and not in the Golgi. The human haptoglobin HP*2 allele contains a 1.7-kb intragenic duplication that arose after a unique nonhomologous recombination between the prototype HP*1 alleles.
Sequence Similarities: Belongs to the peptidase S1 family.

分子量

45 kDa

UniProt

P00738

途径

Transition Metal Ion Homeostasis