NME1 抗体 (C-Term)
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北京 101111
Quick Overview for NME1 抗体 (C-Term) (ABIN3044197)
抗原
See all NME1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-NM23A/NME1 Antibody
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序列
- EELVDYTSCA QNWIYE
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by two amino acids,from rat sequence by one amino acid.
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产品特性
- Anti-NM23A/NME1 Antibody. Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human NM23A, different from the related mouse sequence by two amino acids and from rat sequence by one amino acid.
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亚型
- IgG
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anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 43-152) antibody
NME1 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) antibodyNME1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyNME1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyKD Validated NME1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2195 unconjugated Recombinant Antibody
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyNME1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4B2 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 6-147) antibodyNME1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠 WB, IHC, DB 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, 犬, 猴, Pig, Cow, 马, 兔, 小鸡, 非洲爪蟾, 斑马鱼, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (C-Term) antibodyNME1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Human, Rat, MouseImmunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human Immunocytochemistry, 0.5-1 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma." in: Molecular and clinical oncology, Vol. 5, Issue 1, pp. 107-110, (2016) (PubMed).
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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别名
- NME1
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背景
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Background: NME1 (NME/NM23 nucleoside diphosphate kinase 1) also called non-metastatic cells 1, protein (NM23A) expressed in,NM23, NM23-H1, NDPKA, GAAD or AWD, is an enzyme that in humans is encoded by the NME1 gene. The promoters of the mouse and human NME1 genes, like those of other NME genes, contain several binding sites for AP2, NF1, Sp1, LEF1, and response elements to glucocorticoid receptors. The NME1 gene is mapped on 17q21.33. Immunofluorescence microscopy demonstrated colocalization of NME1 in nuclei of B cells expressing EBNA3C. Expression of EBNA3C reversed the ability of NME1 to inhibit migration of BL and breast carcinoma cells. NM23H1 bound SET and was released from inhibition by GZMA cleavage of SET. After GZMA loading or cytotoxic T lymphocyte attack, SET and NM23H1 translocated to the nucleus and SET was degraded, allowing NM23H1 to nick chromosomal DNA. Using a Drosophila model system, Dammai et al. (2003) showed that the Drosophila NME1 homolog, awd, regulates trachea cell motility by modulating FGFR levels through a dynamin -mediated pathway.
Gene Full Name: NME/NM23 nucleoside diphosphate kinase 1
Sequence Similarities: Belongs to the NDK family.
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分子量
- 17 kDa
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基因ID
- 4830
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UniProt
- P15531
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途径
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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