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MAG 抗体 (N-Term)

Name: MAG 抗体 (N-Term)
SKU: ABIN3044143
Availability: OutOfStock

MAG 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Anti-MAG antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Rat Brain Tissue Lysate Lane 3: Mouse Brain Tissue Lysate Lane 4: Mouse Brain Tissue Lysate (MAG 抗体 (N-Term))

Observed bind size: 100KD (MAG 抗体 (N-Term))

Anti-MAG antibody, IHC(P) IHC(P): Rat Brain Tissue (MAG 抗体 (N-Term))

IHC

Anti-MAG antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (MAG 抗体 (N-Term))

IHC

4 images

产品编号 ABIN3044143

发货至: 中国

Datasheet as PDF

抗原 See all MAG 抗体

MAG (Myelin Associated Glycoprotein (MAG))
抗原表位
14

8

7

5

2

2

2

2

2

2

1

1

1

1
AA 114-132, N-Term
适用
58

32

28

3

2

2

1

1

1

1

1

1

1
小鼠, 大鼠
宿主
50

10
兔
Compatible Secondaries
克隆类型
50

10
多克隆
标记
32

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MAG antibody is un-conjugated
应用范围
51

28

12

12

11

11

10

4

3

3

3

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Myelin-associated glycoprotein MAG Antibody Picoband®

序列

KYYFRGDLGG YNQYTFSEH

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Myelin-associated glycoprotein MAG Antibody (ABIN3044143). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human MAG, identical to the related rat and mouse sequences.

亚型

IgG

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anti-Myelin Associated Glycoprotein (MAG) (AA 119-208) antibody
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anti-Myelin Associated Glycoprotein (MAG) (AA 439-466) antibody
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anti-Myelin Associated Glycoprotein (MAG) antibody
MAG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

anti-Myelin Associated Glycoprotein (MAG) (AA 501-582) antibody
MAG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myelin Associated Glycoprotein (MAG) (AA 551-626) antibody
MAG 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myelin Associated Glycoprotein (MAG) (C-Term) antibody
MAG 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myelin Associated Glycoprotein (MAG) (AA 119-209) antibody
MAG 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated

anti-Myelin Associated Glycoprotein (MAG) (C-Term) antibody
MAG 适用: 人, 大鼠 WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. Atwal, J. K., Pinkston-Gosse, J., Syken, J., Stawicki, S., Wu, J., Shatz, C., Tessier-Lavigne, M. PirB is a functional receptor for myelin inhibitors of axonal regeneration. Science 322: 967-970, 2008. 2. Barton, D. E., Arquint, M., Roder, J., Dunn, R., Francke, U. The myelin-associated glycoprotein gene: mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice. Genomics 1: 107-112, 1987. 3. Liu, B. P., Fournier, A., GrandPre, T., Strittmatter, S. M. Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor. Science 297: 1190-1193, 2002.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

MAG (Myelin Associated Glycoprotein (MAG))

别名

MAG (MAG 产品)

背景

Synonyms: Myelin-associated glycoprotein,Siglec-4a,MAG,GMA,
Background: MAG (Myelin-associated glycoprotein),also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is though to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR. MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner. Experiments blocking NgR from interacting with MAG prevented inhibition of neurite outgrowth by MAG. In cultured human embryonic kidney (HEK) cells expressing the NOGO receptor, p75 (NTR) was required for MAG-induced intracellular calcium elevation.
Sequence Similarities: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

分子量

100 kDa

UniProt

P20916

途径

Neurotrophin Signaling Pathway