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DLL3 抗体 (C-Term)

DLL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044121
发货至: 中国
  • 抗原 See all DLL3 抗体
    DLL3 (delta Like Protein 3 (DLL3))
    抗原表位
    • 10
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 599-618, C-Term
    适用
    • 52
    • 24
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 53
    • 2
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 22
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLL3 antibody is un-conjugated
    应用范围
    • 50
    • 27
    • 21
    • 19
    • 10
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Delta-like protein 3(DLL3) detection. Tested with WB in Human.
    序列
    RAGQRQHLLF PYPSSILSVK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Delta-like protein 3(DLL3) detection. Tested with WB in Human.
    Gene Name: delta-like 3(Drosophila)
    Protein Name: Delta-like protein 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human DLL3(599-618aa RAGQRQHLLFPYPSSILSVK).
    亚型
    IgG
    Top Product
    Discover our top product DLL3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for DLL3 is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    DLL3 (delta Like Protein 3 (DLL3))
    别名
    DLL3 (DLL3 产品)
    别名
    SCDO1 antibody, pu antibody, pudgy antibody, delta like canonical Notch ligand 3 antibody, delta-like 3 (Drosophila) antibody, DLL3 antibody, Dll3 antibody
    背景
    DLL3(DELTA-LIKE 3) also known as DELTA, DROSOPHILA, HOMOLOG OF, is a protein which in humans is encoded by the DLL3 gene. This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutation in the mouse delta-like 3 gene(Dll3), which is homologous to the Notch-ligand delta in Drosophila, results in the mouse 'pudgy' phenotype. The human DLL3 gene was identified within a critical interval, mapped in 2 consanguineous Arab-Israeli and Pakistani SCDO1 pedigrees, of 7.8 cM at 19q13.1-q13.3 between D19S570 and D19S908(Bulman et al., 2000). Dunwoodie et al.(1997) presented results suggesting that mouse Dll3 may complement the function of other delta homologs during early pattern formation in the mouse embryo. In humans, the fact that mutations in genes required for oscillation, such as DLL3, result in abnormal segmentation of the vertebral column suggests that the segmentation clock also acts during human embryonic development. This residue is highly conserved in Delta proteins from Drosophila to humans, and the substitution of a charged polar for a nonpolar residue may disrupt the conformation of the DLL3 protein.

    Synonyms: Delta Drosophila like 3 antibody|Delta like 3 Drosophila antibody|Delta like 3 homolog Drosophila antibody|Delta like 3 protein antibody|Delta like protein 3 precursor antibody|Delta-like protein 3 antibody|Delta3 antibody|Dll3 antibody|DLL3_HUMAN antibody|Drosophila Delta homolog 3 antibody|SCDO1 antibody|SCOD1 antibody|Spondylocostal dysostosis autosomal recessive antibody
    途径
    Notch Signaling
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