TGFBR2 抗体 (Middle Region)
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北京 101111
Quick Overview for TGFBR2 抗体 (Middle Region) (ABIN3044092)
抗原
See all TGFBR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-346, Middle Region
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原理
- Anti-TGF beta Receptor II/TGFBR2 Antibody
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序列
- KGNLQEYLTR HVISWED
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-TGF beta Receptor II/TGFBR2 Antibody (ABIN3044092). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TGF beta Receptor II, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 13-40), (N-Term) antibody
TGFBR2 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB31405 unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 241-330) antibodyTGFBR2 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 13-40) antibodyTGFBR2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 25-159) antibodyTGFBR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 62-165) antibodyTGFBR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 60-140) antibodyTGFBR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (pSer225), (pSer250) antibodyTGFBR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 209-590) antibodyTGFBR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 548-575), (C-Term) antibodyTGFBR2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37153 unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 548-575) antibodyTGFBR2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Mechanism Investigation of the Improvement of Chang Run Tong on the Colonic Remodeling in Streptozotocin-Induced Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 1826281, (2016) (PubMed).
: "Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 2601830, (2016) (PubMed).
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: "Mechanism Investigation of the Improvement of Chang Run Tong on the Colonic Remodeling in Streptozotocin-Induced Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 1826281, (2016) (PubMed).
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- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
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别名
- TGFBR2
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背景
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Synonyms: TGF-beta receptor type-2;TGFR-2;2.7.11.30;TGF-beta type II receptor;Transforming growth factor-beta receptor type II;TGF-beta receptor type II;TbetaR-II;TGFBR2;
Tissue Specificity: Abundant in brain.
Background: TGFBR2 (transforming growth factor, beta receptor II (70/80kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II (TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. TGFBR2 may be a target of the EWS-FLI1 fusion protein found in Ewing sarcoma and related peripheral primitive neuroectodermal tumors.
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
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分子量
- 65 kDa
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UniProt
- P37173
抗原
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