Prohibitin 抗体 (C-Term)
(1 reference)-
- 抗原 See all Prohibitin (PHB) 抗体
- Prohibitin (PHB)
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抗原表位
- AA 240-256, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prohibitin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Prohibitin(PHB) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- KLEAAEDIAY QLSRSRN
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Prohibitin(PHB) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: prohibitin
Protein Name: Prohibitin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Prohibitin(240-256aa KLEAAEDIAYQLSRSRN), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product PHB Primary Antibody
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anti-Prohibitin (PHB) (AA 1-272) antibody
PHB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F4-2B2 unconjugated
anti-Prohibitin (PHB) antibodyKO Validated PHB 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) antibodyPHB 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H7 unconjugated
anti-Prohibitin (PHB) (AA 177-272) antibodyPHB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal PHB-3194 unconjugated
anti-Prohibitin (PHB) (AA 73-272) antibodyPHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal PHB-3231 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PHB-3230 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PHB-1881 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PHB-3193 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Positional and expressive alteration of prohibitin during the induced differentiation of human hepatocarcinoma SMMC-7721 cells." in: World journal of gastroenterology, Vol. 14, Issue 32, pp. 5008-14, (2008) (PubMed).
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: "Positional and expressive alteration of prohibitin during the induced differentiation of human hepatocarcinoma SMMC-7721 cells." in: World journal of gastroenterology, Vol. 14, Issue 32, pp. 5008-14, (2008) (PubMed).
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- 抗原
- Prohibitin (PHB)
- 别名
- PHB (PHB 产品)
- 别名
- phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody
- 背景
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PHB(Prohibitin), also known as PHB1, is a protein that in humans is encoded by the PHB gene. White et al.(1991) mapped the PHB gene to chromosome 17 by analysis of human-mouse somatic cell hybrid cell lines using a genomic fragment of human prohibitin DNA isolated from a library using the rat prohibitin cDNA clone. By in situ hybridization, they localized the gene to 17q21. Sato et al.(1992) isolated the human homolog of the rat prohibitin gene and mapped it to 17q12-q21 by in situ hybridization. Proliferation of tumor cells depends on new blood vessel formation(angiogenesis) that accompanies malignant progression. Anticancer therapies using angiogenesis inhibitors or cytotoxic agents targeted to the vasculature of tumors have been evaluated in clinical trials. Although white fat is a nonmalignant tissue, it has the capability to quickly proliferate and expand. Furthermore, it is highly vascularized. Rupnick et al.(2002) showed that nonspecific angiogenesis inhibitors can prevent the development of obesity of mice.
Synonyms: PHB antibody|PHB_HUMAN antibody|PHB1 antibody|prohibitin antibody - UniProt
- P35232
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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