PTH1R 抗体 (C-Term)
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Quick Overview for PTH1R 抗体 (C-Term) (ABIN3043983)
抗原
See all PTH1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 388-406, C-Term
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原理
- Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody
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序列
- KLRETNAGRC DTRQQYRKL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody (ABIN3043983). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Parathyroid Hormone Receptor 1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Parathyroid Hormone 1 Receptor (PTH1R) (pThr1) antibody
PTH1R 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) antibodyPTH1R 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 241-255), (Extracellular) antibodyPTH1R 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 485-593) antibodyPTH1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (N-Term) antibodyPTH1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 146-169) antibodyPTH1R 适用: 人, 小鼠, Cow, Pig, 犬, 猴, 马 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 28-188) antibodyPTH1R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).
: "Effects of Intermittent Administration of Parathyroid Hormone (1-34) on Bone Differentiation in Stromal Precursor Antigen-1 Positive Human Periodontal Ligament Stem Cells." in: Stem cells international, Vol. 2016, pp. 4027542, (2016) (PubMed).
: "TGF-? Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma." in: Journal of Cancer, Vol. 6, Issue 6, pp. 511-8, (2015) (PubMed).
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: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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别名
- PTH1R
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背景
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Synonyms: Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH/PTHrP type I receptor,PTH/PTHr receptor,Parathyroid hormone 1 receptor,PTH1 receptor,PTH1R,PTHR, PTHR1,
Tissue Specificity: Expressed in most tissues. Most abundant in kidney, bone and liver.
Background: Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
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分子量
- 66 kDa
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UniProt
- Q03431
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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