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PTH1R 抗体 (C-Term)

Name: PTH1R 抗体 (C-Term)
SKU: ABIN3043983
Availability: OutOfStock

PTH1R 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 388-406), (C-Term) antibody (ABIN3043983) (PTH1R 抗体 (C-Term))

Anti-Parathyroid Hormone Receptor 1 antibody, IHC(P) IHC(P): Human Thyroid Cancer Tissue (PTH1R 抗体 (C-Term))

IHC

2 images

(3 references)

产品编号 ABIN3043983

发货至: 中国

Datasheet as PDF

抗原 See all PTH1R 抗体

PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
抗原表位
6

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 388-406, C-Term
适用
41

15

9

7

7

6

5

4

2

1

1

1

1

1

1

1

1
人, 大鼠, 小鼠
宿主
34

7

1
兔
Compatible Secondaries
克隆类型
33

9
多克隆
标记
31

2

2

1

1

1

1

1

1

1
This PTH1R antibody is un-conjugated
应用范围
27

19

17

9

6

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

原理

Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody Picoband®

序列

KLRETNAGRC DTRQQYRKL

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody (ABIN3043983). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Parathyroid Hormone Receptor 1, identical to the related mouse and rat sequences.

亚型

IgG

Top Product

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anti-Parathyroid Hormone 1 Receptor (PTH1R) (pThr1) antibody
PTH1R 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) antibody
PTH1R 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4D2 unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 1268-1341) antibody
PTH1R 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) antibody
PTH1R 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 241-255), (Extracellular) antibody
PTH1R 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 485-593) antibody
PTH1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) antibody
PTH1R 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (N-Term) antibody
PTH1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 146-169) antibody
PTH1R 适用: 人, 小鼠, Cow, Pig, 犬, 猴, 马 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Parathyroid Hormone 1 Receptor (PTH1R) (Center) antibody
PTH1R 适用: 人, Cow, Pig, 犬 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Bastepe, M., Raas-Rothschild, A., Silver, J., Weissman, I., Wientroub, S., Juppner, H., Gillis, D. A form of Jansen's metaphyseal chondrodysplasia with limited metabolic and skeletal abnormalities is caused by a novel activating parathyroid hormone (PTH)/PTH-related peptide receptor mutation. J. Clin. Endocr. Metab. 89: 3595-3600, 2004. 2. Decker, E., Stellzig-Eisenhauer, A., Fiebig, B. S., Rau, C., Kress, W., Saar, K., Ruschendorf, F., Hubner, N., Grimm, T., Weber, B. H. F. PTHR1 loss-of-function mutations in familial, nonsyndromic primary failure of tooth eruption. Am. J. Hum. Genet. 83: 781-786, 2008. 3. Hoogendam, J., Farih-Sips, H., Wynaendts, L. C., Lowik, C. W. G. M., Wit, J. M., Karperien, M. Novel mutations in the parathyroid hormone (PTH)/PTH-related peptide receptor type 1 causing Blomstrand osteochondrodysplasia types I and II. J. Clin. Endocr. Metab. 92: 1088-1095, 2007. 4. Wang, B., Yang, Y., Friedman, P. A. Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway. Mol. Biol. Cell 19: 1637-1645, 2008.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Ma, Wu, Jin: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).

Wang, Wang, Dai, Chen, Yang, Dai, Ou, Wang, Lin: "Effects of Intermittent Administration of Parathyroid Hormone (1-34) on Bone Differentiation in Stromal Precursor Antigen-1 Positive Human Periodontal Ligament Stem Cells." in: Stem cells international, Vol. 2016, pp. 4027542, (2016) (PubMed).

Li, He, Yao, Song, Zeng, Peng, Rosol, Deng: "TGF-? Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma." in: Journal of Cancer, Vol. 6, Issue 6, pp. 511-8, (2015) (PubMed).
抗原

PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

别名

PTH1R (PTH1R 产品)

背景

Synonyms: Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH/PTHrP type I receptor,PTH/PTHr receptor,Parathyroid hormone 1 receptor,PTH1 receptor,PTH1R,PTHR, PTHR1,
Tissue Specificity: Expressed in most tissues. Most abundant in kidney, bone and liver.
Background: Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

分子量

66 kDa

UniProt

Q03431

途径

Regulation of Carbohydrate Metabolic Process