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Prolactin Receptor 抗体 (C-Term)

Name: Prolactin Receptor 抗体 (C-Term)
SKU: ABIN3043973
Availability: OutOfStock

PRLR 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Anti-Prolactin Receptor antibody, IHC(P) IHC(P): Rat Testis Tissue (Prolactin Receptor 抗体 (C-Term))

IHC

Anti-Prolactin Receptor antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: MCF-7 Cell Lysate (Prolactin Receptor 抗体 (C-Term))

Anti-Prolactin Receptor antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (Prolactin Receptor 抗体 (C-Term))

IHC

Western blot analysis of PRLR using anti- PRLR antibody . (Prolactin Receptor 抗体 (C-Term))

4 images

(1 reference)

产品编号 ABIN3043973

发货至: 中国

Datasheet as PDF

抗原 See all Prolactin Receptor (PRLR) 抗体

Prolactin Receptor (PRLR)
抗原表位
14

6

5

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 591-605, C-Term
适用
79

30

22

3

2

1

1

1

1

1

1

1
人, 大鼠, 小鼠
宿主
51

30

5

2

1
兔
Compatible Secondaries
克隆类型
49

37

2
多克隆
标记
47

7

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Prolactin Receptor antibody is un-conjugated
应用范围
49

25

23

21

19

18

12

12

11

10

10

5

3

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Prolactin Receptor/PRLR Antibody Picoband®

序列

QLGRLDYLDP TCFMH

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Prolactin Receptor/PRLR Antibody (ABIN3043973). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of mouse PRLR, identical to the related rat sequence, and different from the related human sequence by three amino acids.

亚型

IgG

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anti-Prolactin Receptor (PRLR) (AA 20-229) antibody
PRLR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Prolactin Receptor (PRLR) (C-Term) antibody
PRLR 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Prolactin Receptor (PRLR) (AA 1-622) antibody
PRLR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Prolactin Receptor (PRLR) (AA 371-479) antibody
PRLR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated

anti-Prolactin Receptor (PRLR) antibody
PRLR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rPRLR-742 unconjugated Recombinant Antibody

anti-Prolactin Receptor (PRLR) (AA 251-350) antibody
PRLR 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Prolactin Receptor (PRLR) antibody
PRLR 适用: 人 IHC, StM 宿主: 兔 Monoclonal PRLR-3785R unconjugated Recombinant Antibody

anti-Prolactin Receptor (PRLR) (AA 330-548) antibody
PRLR 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Prolactin Receptor (PRLR) antibody
PRLR 适用: 人 FACS, IF, IHC, IHC (p), StM 宿主: 小鼠 Monoclonal SPM213 unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Arden, K. C., Boutin, J.-M., Djiane, J., Kelly, P. A., Cavenee, W. K. The receptors for prolactin and growth hormone are localized in the same region of human chromosome 5. Cytogenet. Cell Genet. 53: 161-165, 1990. 2. Arden, K. C., Cavenee, W. K., Boutin, J.-M., Kelly, P. A. The genes encoding the receptors for prolactin and growth hormone map to human chromosome 5. (Abstract) Am. J. Hum. Genet. 45 (suppl.): A129 only, 1989. 3. Cunningham, B. C., Bass, S., Fuh, G., Wells, J. A. Zinc mediation of the binding of human growth hormone to the human prolactin receptor. Science 250: 1709-1712, 1990.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." in: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).
抗原

Prolactin Receptor (PRLR)

别名

PRLR (PRLR 产品)

背景

Synonyms: Prolactin receptor,PRL-R,Prlr,
Tissue Specificity: Expressed abundantly in the testis. .
Background: PRLR (Prolactin Receptor), is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al. (1989, 1990) demonstrated that the prolactin receptor gene resides in the same chromosomal region as the growth hormone receptor gene, which has been mapped to 5p13-p12. Cunningham et al. (1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to the growth hormone receptor or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues (histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR (conserved in all PRL receptors but not GH receptors) are likely zinc-ion ligands.
Sequence Similarities: Belongs to the type I cytokine receptor family. Type 1 subfamily.

分子量

95 kDa

UniProt

Q08501

途径

JAK/STAT Signaling, Response to Growth Hormone Stimulus