Peroxiredoxin 3 抗体 (AA 110-256)
Our Local Distributor
北京 101111
Quick Overview for Peroxiredoxin 3 抗体 (AA 110-256) (ABIN3043904)
抗原
See all Peroxiredoxin 3 (PRDX3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 110-256
-
原理
- Anti-Peroxiredoxin 3/PRDX3 Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Peroxiredoxin 3/PRDX3 Antibody (ABIN3043904). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Peroxiredoxin 3 recombinant protein (Position: T110-Q256). Human Peroxiredoxin 3 shares 93% amino acid (aa) sequence identity with both mouse and rat Peroxiredoxin 3.
-
亚型
- IgG
-
-
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibody
PRDX3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 5-233) antibodyPRDX3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyKD Validated PRDX3 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB935 unconjugated Recombinant Antibody
anti-Peroxiredoxin 3 (PRDX3) (AA 63-256) antibodyPRDX3 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibodyPRDX3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 239-256) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibodyPRDX3 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1E3-B2 unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyPRDX3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Peroxiredoxin 3 (PRDX3)
-
别名
- PRDX3
-
背景
-
Synonyms: Thioredoxin-dependent peroxide reductase, mitochondrial,1.11.1.15,Antioxidant protein 1,AOP-1,HBC189,Peroxiredoxin III,Prx-III,Peroxiredoxin-3,Protein MER5 homolog,PRDX3,AOP1,
Tissue Specificity: Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.
Background: PRDX3 (peroxiredoxin 3) also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human AOP1 protein shares 86 % amino acid sequence similarity with mouse Aop1, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that PRDX3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.
Sequence Similarities: Belongs to the AhpC/TSA family.
-
分子量
- 25 kDa
-
基因ID
- 10935
-
UniProt
- P30048
-
途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
-
