POMC 抗体 (Middle Region)
(2 references)-
- 抗原 See all POMC 抗体
- POMC (Proopiomelanocortin (POMC))
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抗原表位
- AA 138-176, Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POMC antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 原理
- Anti-ACTH/POMC Antibody
- 序列
- SYSMEHFRWG KPVGKKRRPV KVYPNGAEDE SAEAFPLEF
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-ACTH/POMC Antibody Picoband® (ABIN3043901). Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human ACTH, different from the related mouse and rat sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product POMC Primary Antibody
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anti-Proopiomelanocortin (POMC) (C-Term) antibody
Verified POMC 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (N-Term) antibodyPOMC 适用: 人, 小鼠, 大鼠 ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal 57 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D2B5 unconjugated
anti-Proopiomelanocortin (POMC) antibodyPOMC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 205-267) antibodyPOMC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D3A10 unconjugated
anti-Proopiomelanocortin (POMC) (AA 237-267) antibodyPOMC 适用: 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
1. Dibner, Charna, Schibler, Ueli, Albrecht, Urs (2010). "The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks". Annual Review of Physiology72: 517-549. 2. Hanukoglu I, Feuchtwanger R, Hanukoglu A (November 1990). "Mechanism of corticotropin and cAMP induction of mitochondrial cytochrome P450 system enzymes in adrenal cortex cells". J. Biol. Chem. 265 (33): 20602-8. 3. Raikhinstein M, Zohar M, Hanukoglu I (February 1994). "cDNA cloning and sequence analysis of the bovine adrenocorticotropic hormone (ACTH) receptor". Biochim. Biophys. Acta 1220 (3): 329-32. - 说明
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Antibody can be supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury." in: Neural regeneration research, Vol. 7, Issue 22, pp. 1729-35, (2015) (PubMed).
: "Effects of the extract of a Chinese herb Tripterygium wilfordii hook f on rat pituitary gland." in: The American journal of Chinese medicine, Vol. 33, Issue 6, pp. 945-55, (2006) (PubMed).
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: "Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury." in: Neural regeneration research, Vol. 7, Issue 22, pp. 1729-35, (2015) (PubMed).
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- 抗原
- POMC (Proopiomelanocortin (POMC))
- 别名
- POMC (POMC 产品)
- 背景
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Synonyms: Pro-opiomelanocortin,POMC,Corticotropin-lipotropin,NPP,Melanotropin gamma,Gamma-MSH,Potential peptide,Corticotropin,Adrenocorticotropic hormone,ACTH,Melanotropin alpha,Alpha-MSH,Corticotropin-like intermediary peptide,CLIP,Lipotropin beta,Beta-LPH,Lipotropin gamma,Gamma-LPH,Melanotropin beta,Beta-MSH,Beta-endorphin,Met-enkephalin,POMC,
Tissue Specificity: ACTH and MSH are produced by the pituitary gland.
Background: Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. This gene can influence steroid hormone secretion by both rapid short-term mechanisms that take place within minutes and slower long-term actions. Besides, ACTH also enhances transcription of mitochondrial genes that encode for subunits of mitochondrial oxidative phosphorylation systems.
Sequence Similarities: Belongs to the POMC family.
- 分子量
- 30 kDa
- 基因ID
- 5443
- UniProt
- P01189
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
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