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POMC 抗体 (Middle Region)

Name: POMC 抗体 (Middle Region)
SKU: ABIN3043901
Availability: OutOfStock

This anti-POMC antibody is a 兔多克隆 antibody detecting POMC in IHC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 2+ publications.

Anti-ACTH Picoband antibody, IHC(P): Mouse Kidney Tissue (POMC 抗体 (Middle Region))

IHC

Anti-ACTH Picoband antibody, IHC(P): Rat Kidney Tissue (POMC 抗体 (Middle Region))

IHC

Anti-ACTH Picoband antibody, IHC(P): Rat Brain Tissue (POMC 抗体 (Middle Region))

IHC

3 images

(2 references)

产品编号 ABIN3043901

发货至: 中国

Quick Overview for POMC 抗体 (Middle Region) (ABIN3043901)

抗原

See all POMC 抗体

POMC (Proopiomelanocortin (POMC))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This POMC antibody is un-conjugated

应用范围

Immunohistochemistry (IHC)

Discover our top product POMC Primary Antibody

抗原表位
16

10

9

6

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3

2

2

1

1

1

1
AA 138-176, Middle Region

原理

Anti-ACTH/POMC Antibody

序列

SYSMEHFRWG KPVGKKRRPV KVYPNGAEDE SAEAFPLEF

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-ACTH/POMC Antibody Picoband® (ABIN3043901). Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human ACTH, different from the related mouse and rat sequences by two amino acids.

亚型

IgG
anti-Proopiomelanocortin (POMC) (C-Term) antibody
Verified POMC 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Proopiomelanocortin (POMC) (AA 1-267) antibody
POMC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Proopiomelanocortin (POMC) (N-Term) antibody
POMC 适用: 人, 小鼠, 大鼠 ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal 57 unconjugated

anti-Proopiomelanocortin (POMC) (AA 1-150) antibody
POMC 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D2B5 unconjugated

anti-Proopiomelanocortin (POMC) antibody
POMC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Proopiomelanocortin (POMC) (AA 1-267) antibody
POMC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Proopiomelanocortin (POMC) (AA 205-267) antibody
POMC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated

anti-Proopiomelanocortin (POMC) (AA 1-267) antibody
POMC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Proopiomelanocortin (POMC) (AA 1-150) antibody
POMC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D3A10 unconjugated

anti-Proopiomelanocortin (POMC) (AA 27-235) antibody
POMC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
1. Dibner, Charna, Schibler, Ueli, Albrecht, Urs (2010). "The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks". Annual Review of Physiology72: 517-549. 2. Hanukoglu I, Feuchtwanger R, Hanukoglu A (November 1990). "Mechanism of corticotropin and cAMP induction of mitochondrial cytochrome P450 system enzymes in adrenal cortex cells". J. Biol. Chem. 265 (33): 20602-8. 3. Raikhinstein M, Zohar M, Hanukoglu I (February 1994). "cDNA cloning and sequence analysis of the bovine adrenocorticotropic hormone (ACTH) receptor". Biochim. Biophys. Acta 1220 (3): 329-32.

说明

Antibody can be supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Huo, Liu, Wang, Zhang, Wang, Yang, Sun, Xu: "Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury." in: Neural regeneration research, Vol. 7, Issue 22, pp. 1729-35, (2015) (PubMed).

Chen, Wang, Zhao, Zhang, Huang: "Effects of the extract of a Chinese herb Tripterygium wilfordii hook f on rat pituitary gland." in: The American journal of Chinese medicine, Vol. 33, Issue 6, pp. 945-55, (2006) (PubMed).
抗原

POMC (Proopiomelanocortin (POMC))

别名

POMC

背景

Synonyms: Pro-opiomelanocortin,POMC,Corticotropin-lipotropin,NPP,Melanotropin gamma,Gamma-MSH,Potential peptide,Corticotropin,Adrenocorticotropic hormone,ACTH,Melanotropin alpha,Alpha-MSH,Corticotropin-like intermediary peptide,CLIP,Lipotropin beta,Beta-LPH,Lipotropin gamma,Gamma-LPH,Melanotropin beta,Beta-MSH,Beta-endorphin,Met-enkephalin,POMC,
Tissue Specificity: ACTH and MSH are produced by the pituitary gland.
Background: Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. This gene can influence steroid hormone secretion by both rapid short-term mechanisms that take place within minutes and slower long-term actions. Besides, ACTH also enhances transcription of mitochondrial genes that encode for subunits of mitochondrial oxidative phosphorylation systems.
Sequence Similarities: Belongs to the POMC family.

分子量

30 kDa

基因ID

5443

UniProt

P01189

途径

Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour