PAK7 抗体 (N-Term)
Quick Overview for PAK7 抗体 (N-Term) (ABIN3043895)
抗原
See all PAK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-55, N-Term
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原理
- Anti-PAK5/PAK7 Antibody Picoband®
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序列
- DPQEQKFTGL PQQWHSLLAD TANRPKPMVD
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PAK5/PAK7 Antibody Picoband® (ABIN3043895). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PAK5, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157) antibody
PAK7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1235 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 621-719) antibodyPAK7 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157), (N-Term) antibodyPAK7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34659 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 600-700) antibodyPAK7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: PAK7 p21(CDKN1A)-activated kinase 7". 2. Dan C, Nath N, Liberto M, Minden A (Dec 2001). "PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells". Mol Cell Biol 22 (2): 567-77. 3. Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (Jan 2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 6 (5): 337-45. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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别名
- PAK5
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背景
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Synonyms: Serine/threonine-protein kinase PAK 7,2.7.11.1,p21-activated kinase 5,PAK-5,p21-activated kinase 7,PAK-7,PAK7,KIAA1264, PAK5,
Tissue Specificity: Predominantly expressed in brain.
Background: Serine/threonine-protein kinase PAK 7, also known as PAK5, is an enzyme that in humans is encoded by the PAK7 gene. The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. And this kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. In addition, this kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
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分子量
- 81 kDa
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基因ID
- 57144
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UniProt
- Q9P286
抗原
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