NOD1 抗体 (AA 1-160)
Quick Overview for NOD1 抗体 (AA 1-160) (ABIN3043890)
抗原
See all NOD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-160
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原理
- Anti-CARD4/NOD1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CARD4/NOD1 Antibody Picoband® (ABIN3043890). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CARD4 recombinant protein (Position: M1-M160). Human CARD4 shares 82% amino acid (aa) sequence identity with mouse CARD4.
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亚型
- IgG
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anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-270) antibody
NOD1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-160) antibodyNOD1 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 51-150) antibodyNOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (C-Term) antibodyNOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951), (C-Term) antibodyNOD1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29527 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951) antibodyNOD1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-93) antibodyNOD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (C-Term) antibodyNOD1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 612-826) antibodyNOD1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951), (C-Term) antibodyNOD1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21998 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Western blot, 0.1-0.5 μg/mL
1. Chamaillard, M., Hashimoto, M., Horie, Y., Masumoto, J., Su, Q., Saab, L., Ogura, Y., Kawasaki, A., Fukase, K., Kusumoto, S., Valvano, M. A., Foster, S. J., Mak, T. W., Nunez, G., Inohara, N. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nature Immun. 4: 702-707, 2003. 2. da Silva Correia, J., Miranda, Y., Austin-Brown, N., Hsu, J., Mathison, J., Xiang, R., Zhou, H., Li, Q., Han, J., Ulevitch, R. J. Nod1-dependent control of tumor growth. Proc. Nat. Acad. Sci. 103: 1840-1845, 2006. 3. Martinon F, Tschopp J (2006). "NLRs join TLRs as innate sensors of pathogens.".Trends Immunol. 26 (8): 447-54. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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别名
- NOD1
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背景
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Synonyms: Nucleotide-binding oligomerization domain-containing protein 1,Caspase recruitment domain-containing protein 4,NOD1,CARD4,
Tissue Specificity: Highly expressed in adult heart, skeletal muscle, pancreas, spleen and ovary. Also detected in placenta, lung, liver, kidney, thymus, testis, small intestine and colon.
Background: Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.
Sequence Similarities: Contains 1 CARD domain.
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分子量
- 107 kDa
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基因ID
- 10392
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UniProt
- Q9Y239
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
抗原
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