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IDO1 抗体 (N-Term)

Name: IDO1 抗体 (N-Term)
SKU: ABIN3043857
Availability: OutOfStock

IDO1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti- IDO1 Picoband antibody, Western blottingAll lanes: Anti IDO1 at 0. (IDO1 抗体 (N-Term))

IHC (p)

2 images

(1 reference)

产品编号 ABIN3043857

发货至: 中国

Datasheet as PDF

抗原 See all IDO1 抗体

IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
抗原表位
16

11

5

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1
AA 37-69, N-Term
适用
72

31

16

8

1

1

1
人, 小鼠, 大鼠
宿主
66

12

1

1
兔
Compatible Secondaries
克隆类型
63

17

1
多克隆
标记
52

5

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This IDO1 antibody is un-conjugated
应用范围
64

36

25

18

16

15

14

9

6

6

3

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Indoleamine 2,3-dioxygenase 1(IDO1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

序列

NDWMFIAKHL PDLIESGQLR ERVEKLNMLS IDH

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Indoleamine 2,3-dioxygenase 1(IDO1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: indoleamine 2,3-dioxygenase 1
Protein Name: Indoleamine 2,3-dioxygenase 1

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human IDO1 (37-69aa NDWMFIAKHLPDLIESGQLRERVEKLNMLSIDH), different from the related mouse sequence by fourteen amino acids, and from the related rat sequence by seventeen amino acids.

亚型

IgG

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IDO1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D2 unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibody
Verified IDO1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibody
IDO1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibody
IDO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibody
IDO1 适用: 小鼠 WB, ELISA, IHC, IF, FACS, IP, FM, MA 宿主: 小鼠 Monoclonal 2E2-6 unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-100) antibody
IDO1 适用: 人, 小鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) antibody
IDO1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C5 unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibody
IDO1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 204-403) antibody
IDO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibody
IDO1 适用: 小鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Li, Xu, Bai, Yang, Zhao, Zhang, Chen, Wang: "Umbilical Cord Tissue-Derived Mesenchymal Stem Cells Induce T Lymphocyte Apoptosis and Cell Cycle Arrest by Expression of Indoleamine 2, 3-Dioxygenase." in: Stem cells international, Vol. 2016, pp. 7495135, (2016) (PubMed).
抗原

IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

别名

IDO1 (IDO1 产品)

背景

IDO1 (INDOLEAMINE 2,3-DIOXYGENASE), INDO or IDO, is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells. This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine. By fluorescence in situ hybridization, the assignment is narrowed to chromosome 8p12-p11. INDO Interferon-gamma has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase. During inflammation, IDO is upregulated in dendritic cells and phagocytes by proinflammatory stimuli, most notably IFNG, and the enzyme then uses superoxide as a 'cofactor' for oxidative cleavage of the indole ring of tryptophan, yielding an intermediate that deformylates to L-kynurenine.

Synonyms: 3-dioxygenase antibody|I23O1_HUMAN antibody|IDO 1 antibody|IDO antibody|IDO-1 antibody|IDO1 antibody|INDO antibody|indolamine 2,3 dioxygenase antibody|Indole 2 3 dioxygenase antibody|indoleamine 2 3 dioxygenase 1 antibody|indoleamine 2 3 dioxygenase antibody| Indoleamine 2,3-dioxygenase 1 antibody|Indoleamine pyrrole 2 3 dioxygenase antibody|Indoleamine-pyrrole 2 antibody

基因ID

3620

UniProt

P14902

途径

Activated T Cell Proliferation