GSTA1 抗体 (N-Term)
Quick Overview for GSTA1 抗体 (N-Term) (ABIN3043839)
抗原
See all GSTA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-97, N-Term
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原理
- Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody Picoband®
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序列
- MKLVQTRAIL NYIASKYNLY GKDIKERALI DM
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody Picoband® (ABIN3043839). Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GSTA1/A2/A3/A4/A5, different from the related mouse and rat sequences by five amino acids.
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亚型
- IgG
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anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-222) antibody
GSTA1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-222) antibodyGSTA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) antibodyGSTA1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-223) antibodyGSTA1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-222) antibodyGSTA1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (N-Term) antibodyGSTA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) antibodyGSTA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB22670 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Immunofluorescence, 2 μg/mL, Mouse, Rat
1. Atkinson, HJ, Babbitt, PC (Nov 24, 2009). "Glutathione transferases are structural and functional outliers in the thioredoxin fold.". Biochemistry 48 (46): 11108-16. 2. Boyer TD (March 1989). "The glutathione S-transferases: an update". Hepatology 9(3): 486-96. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))
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别名
- GSTA1
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背景
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Synonyms: Glutathione S-transferase A1, 2.5.1.18, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1,
Tissue Specificity: Liver.
Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
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分子量
- 26 kDa
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基因ID
- 2938, 2939, 2940
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UniProt
- P08263
抗原
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