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Glutamate Receptor 1 抗体 (AA 19-360)

Name: Glutamate Receptor 1 抗体 (AA 19-360)
SKU: ABIN3043837
Availability: OutOfStock

GLUR1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Anti- GRIA1 antibody, Western blotting All lanes: Anti GRIA1 at 0. (Glutamate Receptor 1 抗体 (AA 19-360))

Anti- GRIA1 antibody, IHC(P) IHC(P): Human Meningeoma Tissue (Glutamate Receptor 1 抗体 (AA 19-360))

IHC

Anti- GRIA1 antibody, IHC(P) IHC(P): Mouse Brain Tissue (Glutamate Receptor 1 抗体 (AA 19-360))

IHC

Anti- GRIA1 antibody, IHC(P) IHC(P): Rat Brain Tissue (Glutamate Receptor 1 抗体 (AA 19-360))

IHC

5 images

(1 reference)

产品编号 ABIN3043837

发货至: 中国

Datasheet as PDF

抗原 See all Glutamate Receptor 1 (GLUR1) 抗体

Glutamate Receptor 1 (GLUR1)
抗原表位
16

15

14

14

13

11

10

7

6

5

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 19-360
适用
102

99

84

6

4

3

3

3

2

1

1

1
人, 大鼠, 小鼠
宿主
113

25

1

1
兔
Compatible Secondaries
克隆类型
102

38
多克隆
标记
67

8

5

5

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

1

1

1

1

1
This Glutamate Receptor 1 antibody is un-conjugated
应用范围
95

37

37

35

33

24

14

13

11

5

4

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband® (ABIN3043837). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.

亚型

IgG

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anti-Glutamate Receptor 1 (GLUR1) (pSer845) antibody
GLUR1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor 1 (GLUR1) antibody
Microarray verified GLUR1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB177574 unconjugated

anti-Glutamate Receptor 1 (GLUR1) (C-Term) antibody
GLUR1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (HRP)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 HRP

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (Biotin)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 Biotin

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (FITC)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 FITC

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (PE)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 PE

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (PerCP)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 PerCP

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (APC)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 APC

anti-Glutamate Receptor 1 (GLUR1) (AA 1-389) antibody (Atto 594)
GLUR1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S355-1 Atto 594

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Lee, H.-K., Takamiya, K., Han, J.-S., Man, H., Kim, C.-H., Rumbaugh, G., Yu, S., Ding, L., He, C., Petralia, R. S., Wenthold, R. J., Gallagher, M., Huganir, R. L.Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory.Cell 112: 631-643, 2003. 2. McLaughlin, D. P., Cheetham, M. E., Kerwin, R. W.Expression of alternatively-spliced glutamate receptors in human hippocampus.Europ. J. Pharm. 244: 89-92, 1993.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Liu, Mei, Li, Roboti, Pang, Ying, Gao, Lowe, Bao: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).
抗原

Glutamate Receptor 1 (GLUR1)

别名

GRIA1 (GLUR1 产品)

背景

Synonyms: Glutamate receptor 1,GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic, AMPA 1,GluA1,GRIA1,GLUH1, GLUR1,
Tissue Specificity: Widely expressed in brain.
Background: GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

分子量

101 kDa

基因ID

2890

UniProt

P42261

途径

PI3K-Akt Signaling