CD46 抗体 (C-Term)
Quick Overview for CD46 抗体 (C-Term) (ABIN3043806)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 366-392, C-Term
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原理
- Anti-CD46 Antibody
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序列
- YRYLQRRKKK GTYLTDETHR EVKFTSL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CD46 Antibody (ABIN3043806). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CD46.
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亚型
- IgG
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anti-CD46 (CD46) (AA 40-320) antibody
CD46 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) antibodyKD Validated CD46 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 23GB5720 unconjugated Recombinant Antibody
anti-CD46 (CD46) (AA 317-343) antibodyCD46 适用: 人 WB, FACS, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 适用: 人, 小鼠 WB, FACS, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (Biotin)CD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 Biotin
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CD46
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别名
- CD46
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背景
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Synonyms: Membrane cofactor protein,TLX,Trophoblast leukocyte common antigen,CD46,CD46,MCP, MIC10,
Tissue Specificity: Expressed by all cells except erythrocytes.
Background: CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Sequence Similarities: Contains 4 Sushi (CCP/SCR) domains.
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分子量
- 50 kDa
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基因ID
- 4179
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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