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Ataxin 3 抗体 (C-Term)

Name: Ataxin 3 抗体 (C-Term)
SKU: ABIN3043796
Availability: OutOfStock

The 兔多克隆 anti-Ataxin 3 antibody is suitable to detect Ataxin 3 in samples from 人和大鼠. It has been validated for WB, IHC, IF, FACS 和 ICC.

Western blot analysis of Ataxin 3 using anti-Ataxin 3 antibody . (Ataxin 3 抗体 (C-Term))

IF analysis of ATXN3 using anti-ATXN3 antibody (ABIN3043796). (Ataxin 3 抗体 (C-Term))

IHC

Anti- Ataxin 3 Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue (Ataxin 3 抗体 (C-Term))

IHC

Flow Cytometry analysis of A549 cells using anti-ATXN3 antibody (ABIN3043796). (Ataxin 3 抗体 (C-Term))

FACS

4 images

产品编号 ABIN3043796

发货至: 中国

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中国
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Quick Overview for Ataxin 3 抗体 (C-Term) (ABIN3043796)

抗原

See all Ataxin 3 (ATXN3) 抗体

Ataxin 3 (ATXN3)

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Ataxin 3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Discover our top product ATXN3 Primary Antibody

抗原表位
15

12

8

7

6

4

3

2

2

2

2

1

1

1

1

1
C-Term

原理

Anti-Ataxin 3/ATXN3 Antibody

序列

EEDLQRALAL SRQEIDMEDE EADLRRAIQ

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

different from the related mouse,rat sequences by two amino acids.

产品特性

Anti-Ataxin 3/ATXN3 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 3, different from the related mouse and rat sequences by two amino acids.

亚型

IgG
anti-Ataxin 3 (ATXN3) (AA 1-364) antibody
ATXN3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) (AA 261-288) antibody
ATXN3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23951 unconjugated

anti-Ataxin 3 (ATXN3) antibody
ATXN3 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) (AA 1-288) antibody
ATXN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) antibody
KO Validated ATXN3 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) (AA 267-297), (Middle Region) antibody
ATXN3 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) (AA 35-84) antibody
ATXN3 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 马, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) (AA 29-59), (N-Term) antibody
ATXN3 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB4606 unconjugated

anti-Ataxin 3 (ATXN3) (AA 120-250) antibody
ATXN3 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 马, 兔, 豚鼠, 犬, 猴, Pig, Cat, 小鸡, 驴, 山羊, Hamster, Avian WB 宿主: 山羊 Polyclonal unconjugated

anti-Ataxin 3 (ATXN3) (N-Term) antibody
ATXN3 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 马, 兔, 豚鼠, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

Ataxin 3 (ATXN3)

别名

ATXN3

背景

Background: ATXN3 (Ataxin 3), also known as AT3, MJD GENE, MJD1, SCA3 GENE, ATX3, JOS, Spinocerebellar ataxia-3, Machado-Joseph disease protein 1, is a protein that in humans is encoded by the ATXN3 gene. ATXN3 ranges in size from 360 to 374 amino acids. Using Northern blot analysis showed that ATXN3 mRNA was ubiquitously expressed in human tissues. They detected at least 4 ATXN3 transcripts of 1.4, 1.8, 4.5, and 7.5 kb and suggested that the different mRNA species probably result from differential splicing and polyadenylation. Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by the ATXN3 gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is an inverse correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Ataxin-3 interacted with 2 human homologs of the yeast DNA repair protein RAD23, HHR23A (RAD23A) and HHR23B (RAD23B). Both normal and mutant ataxin-3 proteins interacted with the ubiquitin-like domain at the N terminus of the HHR23 proteins, which is a motif important for nucleotide excision repair. However, in HEK 293 cells, HHR23A was recruited to intranuclear inclusions formed by the mutant ataxin-3 through its interaction with ataxin-3.
Gene Full Name: ataxin 3
Sequence Similarities: Contains 1 Josephin domain.

分子量

42 kDa

基因ID

4287

UniProt

P54252