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Aspartate beta Hydroxylase 抗体 (C-Term)

ASPH 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043790
发货至: 中国
  • 抗原 See all Aspartate beta Hydroxylase (ASPH) 抗体
    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
    抗原表位
    • 15
    • 7
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    • 6
    • 6
    • 6
    • 4
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    • 1
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    AA 726-758, C-Term
    适用
    • 64
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 58
    • 6
    克隆类型
    • 61
    • 3
    多克隆
    标记
    • 33
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Aspartate beta Hydroxylase antibody is un-conjugated
    应用范围
    • 46
    • 26
    • 25
    • 13
    • 13
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Aspartyl/asparaginyl beta-hydroxylase(ASPH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    EVWQDASSFR LIFIVDVWHP ELTPQQRRSL PAI
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Aspartyl/asparaginyl beta-hydroxylase(ASPH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: aspartate beta-hydroxylase
    Protein Name: Aspartyl/asparaginyl beta-hydroxylase
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human ASPH (726-758aa EVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI), identical to the related mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product ASPH Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
    别名
    ASPH (ASPH 产品)
    别名
    AAH antibody, BAH antibody, CASQ2BP1 antibody, HAAH antibody, JCTN antibody, junctin antibody, 2310005F16Rik antibody, 3110001L23Rik antibody, AI848629 antibody, AW261690 antibody, AW561901 antibody, C79816 antibody, cI-37 antibody, aah antibody, bah antibody, jctn antibody, MGC107896 antibody, cb971 antibody, fb69e10 antibody, fc06d04 antibody, fc95a08 antibody, wu:fb69e10 antibody, wu:fc06d04 antibody, wu:fc95a08 antibody, aspartate beta-hydroxylase antibody, aspartate-beta-hydroxylase antibody, aspartate beta-hydroxylase L homeolog antibody, ASPH antibody, Asph antibody, asph antibody, asph.L antibody
    背景
    ASPH is also known as Aspartyl/asparaginyl beta-hydroxylase. This gene is thought to play an important role in calcium homeostasis. And the gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.

    Synonyms: A beta H J J antibody|AAH antibody|ASP beta hydroxylase antibody|Aspartyl/asparaginyl beta hydroxylase antibody|ASPH antibody|ASPH_HUMAN antibody|BAH antibody|Cardiac junctin antibody|CASQ2BP1 antibody|HAAH antibody|Humbug antibody|JCTN antibody|junctin antibody| Peptide aspartate beta dioxygenase antibody
    基因ID
    444
    UniProt
    Q12797
    途径
    Positive Regulation of Endopeptidase Activity
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