Aspartate beta Hydroxylase 抗体 (N-Term)
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Quick Overview for Aspartate beta Hydroxylase 抗体 (N-Term) (ABIN2784532)
抗原
See all Aspartate beta Hydroxylase (ASPH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ASPH Antibody - N-terminal region
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序列
- MAEDKETKHG GHKNGRKGGL SGTSFFTWFM VIALLGVWTS VAVVWFDLVD
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预测反应
- Cow: 86%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ASPH. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ASPH
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51356-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
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别名
- ASPH
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背景
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Background Information: ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.
Gene Name: Aspartate beta-hydroxylase
Alternative Symbols: AAH, BAH, HAAH, JCTN, FDLAB, junctin, CASQ2BP1
Protein Name: Aspartyl/asparaginyl beta-hydroxylase
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分子量
- 25kDa
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基因ID
- 444
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NCBI登录号
- NP_064549
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UniProt
- Q12797
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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