FGF4 抗体 (Middle Region)
Quick Overview for FGF4 抗体 (Middle Region) (ABIN3043756)
抗原
See all FGF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 84-97, Middle Region
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原理
- Anti-Fibroblast growth factor 4 FGF4 Antibody Picoband®
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序列
- RRLYCNVGIG FHLQ
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Fibroblast growth factor 4 FGF4 Antibody (ABIN3043756). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human FGF4, identical to the related rat and mouse sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Huebner, K., Ferrari, A. C., Delli Bovi, P., Croce, C. M., Basilico, C. : The FGF-related oncogene, K-FGF, maps to human chromosome region 11q13, possibly near int-2. Oncogene Res. 3: 263-270, 1988. 2. Adelaide, J., Mattei, M.-G., Marics, I., Raybaud, F., Planche, J., De Lapeyriere, O., Birnbaum, D. : Chromosomal localization of the hst oncogene and its co-amplification with the int.2 oncogene in a human melanoma. Oncogene 2: 413-416, 1988. 3. Yoshida, T., Tsutsumi, M., Sakamoto, H., Miyagawa, K., Teshima, S., Sugimura, T., Terada, M. : Expression of the HST1 oncogene in human germ cell tumors. Biochem. Biophys. Res. Commun. 155: 1324-1329, 1988. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FGF4 (Fibroblast Growth Factor 4 (FGF4))
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别名
- FGF4
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背景
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Synonyms: Fibroblast growth factor 4,FGF-4,Heparin secretory-transforming protein 1,HST,HST-1,HSTF-1,Heparin-binding growth factor 4,HBGF-4,Transforming protein KS3,FGF4,HST, HSTF1, KS3,
Tissue Specificity: Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level). .
Background: Fibroblast growth factor 4 (FGF4), also known as Heparin Secretary Transforming (HSTF1). HST1, for which the designation HSTF1 was proposed for human gene nomenclature, is a heparin-binding growth factor with significant homology to human fibroblast growth factors and the mouse Int-2 protein. By in situ hybridization, Adelaide et al. (1988) mapped the HST gene to chromosome 11q13. The HST1 protein is a heparin-binding growth factor with significant homology with human fibroblast growth factors and the mouse Int-2 protein.
Sequence Similarities: Belongs to the dUTPase family.
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分子量
- 27 kDa
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UniProt
- P08620
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance
抗原
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