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Nerve Growth Factor 抗体 (N-Term)

NGF 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043754
发货至: 中国
  • 抗原 See all Nerve Growth Factor (NGF) 抗体
    Nerve Growth Factor (NGF)
    抗原表位
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-173, N-Term
    适用
    • 65
    • 40
    • 38
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 69
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 61
    • 29
    • 1
    多克隆
    标记
    • 57
    • 10
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Nerve Growth Factor antibody is un-conjugated
    应用范围
    • 49
    • 45
    • 22
    • 10
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Anti-Beta-nerve growth factor NGF Antibody Picoband®
    序列
    EVNINNSVFK QY
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-Beta-nerve growth factor NGF Antibody (ABIN3043754). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human NGF, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product NGF Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Dracopoli, N. C., Rose, E., Whitfield, G. K., Guidon, P. T., Bale, S. J., Chance, P. A., Kourides, I. A., Housman, D. E. : Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes. Genomics 3: 161-167, 1988. 2. Francke, U., de Martinville, B., Coussens, L., Ullrich, A. : The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. Science 222: 1248-1251, 1983 3. Einarsdottir, E., Carlsson, A., Minde, J., Toolanen, G., Svensson, O., Solders, G., Holmgren, G., Holmberg, D., Holmberg, M. : A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. Hum. Molec. Genet. 13: 799-805, 2004.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Fan, Xiong, Fu, Xu, Wang, Chen, Xia, Peng, Ye, Wang, Zhang, Ye et al.: "Polyaniline promotes peripheral nerve regeneration by enhancement of the brain‑derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling ..." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7534-7540, (2018) (PubMed).

    Luo, Liu, Chen, Wang, Zeng, Chen, Cheng et al.: "Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 ..." in: Neural regeneration research, Vol. 7, Issue 4, pp. 302-7, (2015) (PubMed).

    Zhao, Chen, Shen, Zhao, Wang, Shi, Wang, Cui, Yan, Xue: "Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury." in: Neural regeneration research, Vol. 7, Issue 10, pp. 741-8, (2015) (PubMed).

    Lu, Liu, Zhu, Xu: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, (2014) (PubMed).

    Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).

    Huang, Zhang, Xu, Li, Zhao: "Expression of nerve growth factor in the prostate of male rats in response to chronic stress and sympathetic denervation." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1237-1240, (2014) (PubMed).

    Zhao, Ding, Guo, Chen: "Intrathecal lidocaine neurotoxicity: combination with bupivacaine and ropivacaine and effect of nerve growth factor." in: Life sciences, Vol. 112, Issue 1-2, pp. 10-21, (2014) (PubMed).

    Li, Shu, Tang, Deng, Fu, Lv: "?-Nerve growth factor attenuates hepatocyte injury induced by D-galactosamine in vitro via TrkA NGFR." in: Molecular medicine reports, Vol. 8, Issue 3, pp. 813-7, (2013) (PubMed).

    Pu, Shi, Wang, Wang, Guo, Liu, Sun, Gao, Zhou: "Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats." in: Journal of biomedical research, Vol. 25, Issue 4, pp. 292-8, (2013) (PubMed).

    Sun, Guo, Zheng, Zhang, Li, Liu, Yin, Yang, Shu: "Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy." in: Journal of molecular neuroscience : MN, Vol. 49, Issue 1, pp. 182-93, (2012) (PubMed).

    Orita, Koshi, Mitsuka, Miyagi, Inoue, Arai, Ishikawa, Hanaoka, Yamashita, Yamashita, Eguchi, Toyone, Takahashi, Ohtori: "Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee." in: BMC musculoskeletal disorders, Vol. 12, pp. 144, (2012) (PubMed).

    Wang, Zhao, Fan, Gong, Li, Qi, Liu: "Research on the mechanism of Zuogui Pill and Yougui Pill in promoting axonal regeneration in model rats of autoimmune encephalomyelitis." in: Chinese journal of integrative medicine, Vol. 16, Issue 2, pp. 167-72, (2010) (PubMed).

  • 抗原
    Nerve Growth Factor (NGF)
    别名
    NGF (NGF 产品)
    背景

    Synonyms: Beta-nerve growth factor,Beta-NGF,NGF,NGFB,

    Background: Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. The nucleotide sequence of human and mouse beta-NGF are very similar. The beta-subunits of nerve growth factor (NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception.

    Sequence Similarities: Belongs to the NGF-beta family.

    分子量
    60 kDa
    UniProt
    P01138
    途径
    Regulation of Cell Size
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