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Angiopoietin 1 抗体 (AA 16-350)

Name: Angiopoietin 1 抗体 (AA 16-350)
SKU: ABIN3043724
Availability: OutOfStock

ANGPT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Angiopoietin 1 (ANGPT1) (AA 16-350) antibody (ABIN3043724) (Angiopoietin 1 抗体 (AA 16-350))

Anti-Angiopoietin 1 Picoband antibody, All lanes: Anti Angiopoietin1 at 0. (Angiopoietin 1 抗体 (AA 16-350))

2 images

(1 reference)

产品编号 ABIN3043724

发货至: 中国

Datasheet as PDF

抗原 See all Angiopoietin 1 (ANGPT1) 抗体

Angiopoietin 1 (ANGPT1)
抗原表位
15

11

8

8

7

6

5

5

4

4

4

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 16-350
适用
110

35

34

13

6

6

4

3

2

1

1

1

1

1
人
宿主
119

19

1

1
兔
Compatible Secondaries
克隆类型
102

38
多克隆
标记
77

19

10

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Angiopoietin 1 antibody is un-conjugated
应用范围
105

56

33

33

26

15

13

13

8

6

5

3

3

2

2
Western Blotting (WB)

原理

Anti-Angiopoietin 1/ANGPT1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Angiopoietin 1/ANGPT1 Antibody Picoband® (ABIN3043724). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Angiopoietin 1 recombinant protein (Position: H16-N350). Human Angiopoietin 1 shares 96% amino acid (aa) sequence with both mouse and rat Angiopoietin 1.

亚型

IgG

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ANGPT1 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiopoietin 1 (ANGPT1) (AA 16-498) antibody
ANGPT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: ANGPT1 angiopoietin 1". Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. 2. Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S., Sato, T. N., Yancopoulos, G. D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171-1180, 1996. 3. Cheung, A. H., Stewart, R. J., Marsden, P. A. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23. Genomics 48: 389-391, 1998.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Sun, Wang, Cheng, Wang, Li, Xue, Wang, Ai, Zhang, Xu, Wang, Ji: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." in: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).
抗原

Angiopoietin 1 (ANGPT1)

别名

ANGPT1 (ANGPT1 产品)

背景

Synonyms: Angiopoietin-1,ANG-1,ANGPT1,KIAA0003,
Tissue Specificity: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. .
Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.
Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

分子量

65 kDa

基因ID

284

UniProt

Q15389

途径

RTK signaling, Glycosaminoglycan Metabolic Process