Angiopoietin 1 抗体 (AA 16-350)
(1 reference)Quick Overview for Angiopoietin 1 抗体 (AA 16-350) (ABIN3043724)
抗原
See all Angiopoietin 1 (ANGPT1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 16-350
-
原理
- Anti-Angiopoietin 1/ANGPT1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Angiopoietin 1/ANGPT1 Antibody Picoband® (ABIN3043724). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Angiopoietin 1 recombinant protein (Position: H16-N350). Human Angiopoietin 1 shares 96% amino acid (aa) sequence with both mouse and rat Angiopoietin 1.
-
亚型
- IgG
-
-
anti-Angiopoietin 1 (ANGPT1) (AA 304-450) antibody
ANGPT1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 260-400) antibodyANGPT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (Internal Region) antibodyVerified ANGPT1 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 276-375) antibodyANGPT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 284-452) antibodyANGPT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 21-228) antibodyANGPT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 253-429) antibodyANGPT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 284-452) antibodyANGPT1 适用: 人 WB 宿主: 小鼠 Monoclonal E1 unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 148-266) antibodyANGPT1 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 1 (ANGPT1) (AA 16-498) antibodyANGPT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: ANGPT1 angiopoietin 1". Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. 2. Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S., Sato, T. N., Yancopoulos, G. D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171-1180, 1996. 3. Cheung, A. H., Stewart, R. J., Marsden, P. A. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23. Genomics 48: 389-391, 1998. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
-
: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." in: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).
-
: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." in: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).
-
- Angiopoietin 1 (ANGPT1)
-
别名
- ANGPT1
-
背景
-
Synonyms: Angiopoietin-1,ANG-1,ANGPT1,KIAA0003,
Tissue Specificity: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. .
Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.
Sequence Similarities: Contains 1 fibrinogen C-terminal domain.
-
分子量
- 65 kDa
-
基因ID
- 284
-
UniProt
- Q15389
-
途径
- RTK signaling, Glycosaminoglycan Metabolic Process
抗原
-
