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ATG7 抗体 (C-Term)

Name: ATG7 抗体 (C-Term)
SKU: ABIN3043718
Availability: OutOfStock

This anti-ATG7 antibody is a 兔多克隆 antibody detecting ATG7 in WB. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 3+ publications.

Anti- APG7 Picoband antibody, Western blotting All lanes: Anti APG7 at 0. (ATG7 抗体 (C-Term))

1 image

(3 references)

产品编号 ABIN3043718

发货至: 中国

Quick Overview for ATG7 抗体 (C-Term) (ABIN3043718)

抗原

See all ATG7 抗体

ATG7 (ATG7 Autophagy Related 7 (ATG7))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This ATG7 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product ATG7 Primary Antibody

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AA 673-703, C-Term

原理

Anti-Apg7/ATG7 Antibody Picoband®

序列

HSFLEDLTGL TLLHQETQAA EIWDMSDDET I

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Apg7/ATG7 Antibody Picoband® (ABIN3043718). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Apg7, different from the related mouse and rat sequences by two amino acids.

亚型

IgG
anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibody
ATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibody
ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) antibody
ATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibody
ATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: ATG7 ATG7 autophagy related 7 homolog (S. cerevisiae)". 2. Lee, I. H., Kawai, Y., Fergusson, M. M., Rovira, I. I., Bishop, A. J. R., Motoyama, N., Cao, L., Finkel, T. Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. Science 336: 225-228, 2012. Note: Erratum: Science 337: 910 only, 2012. Note: Erratum: Science 341: 457 only, 2013. 3. Tanida, I., Tanida-Miyake, T., Ueno, T., Kominami, E. The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J. Biol. Chem. 276: 1701-1706, 2001.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Shen, Li, Cai, Liu, Wang, Gan, Li, Wang, Sun, Deng, Liu, Li: "Erbin exerts a protective effect against inflammatory bowel disease by suppressing autophagic cell death." in: Oncotarget, Vol. 9, Issue 15, pp. 12035-12049, (2018) (PubMed).

He, Wang, Han, Jin, Li, Wu, Ma, Cheng, Tang, Yang, Liu: "Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta." in: Open biology, Vol. 6, Issue 7, (2017) (PubMed).

Yang, Sheng, Yang, Li, Qin, Yu, Zhang: "Endocan silencing induces programmed cell death in hepatocarcinoma." in: Oncology letters, Vol. 14, Issue 5, pp. 5333-5339, (2017) (PubMed).
抗原

ATG7 (ATG7 Autophagy Related 7 (ATG7))

别名

ATG7

背景

Synonyms: Ubiquitin-like modifier-activating enzyme ATG7,ATG12-activating enzyme E1 ATG7,Autophagy-related protein 7,APG7-like,hAGP7,Ubiquitin-activating enzyme E1-like protein,ATG7,APG7L,
Tissue Specificity: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. .
Background: Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.
Sequence Similarities: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

分子量

78 kDa

基因ID

10533

UniProt

O95352

途径

Response to Water Deprivation, Autophagy