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XAF1 抗体 (C-Term)

XAF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043705
发货至: 中国
  • 抗原 See all XAF1 抗体
    XAF1 (XiAP Associated Factor 1 (XAF1))
    抗原表位
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 283-301, C-Term
    适用
    • 38
    • 13
    • 4
    • 2
    宿主
    • 35
    • 11
    克隆类型
    • 37
    • 9
    多克隆
    标记
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This XAF1 antibody is un-conjugated
    应用范围
    • 26
    • 15
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for XIAP-associated factor 1(XAF1) detection. Tested with WB, IHC-P in Human.
    序列
    QEKCRWLASS KGKQVRNFS
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for XIAP-associated factor 1(XAF1) detection. Tested with WB, IHC-P in Human.
    Gene Name: XIAP associated factor 1
    Protein Name: XIAP-associated factor 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human XAF1(283-301aa QEKCRWLASSKGKQVRNFS).
    亚型
    IgG
    Top Product
    Discover our top product XAF1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    XAF1 (XiAP Associated Factor 1 (XAF1))
    别名
    XAF1 (XAF1 产品)
    别名
    BIRC4BP antibody, HSXIAPAF1 antibody, XIAPAF1 antibody, Fbxo39 antibody, XIAP associated factor 1 antibody, xaf1 antibody, XAF1 antibody, Xaf1 antibody
    背景
    XIAP associated factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis(XIAP, MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP(BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells. And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells.

    Synonyms: BIRC 4 binding protein antibody|BIRC4 binding protein antibody|BIRC4-binding protein antibody|BIRC4BP antibody|HSXIAPAF 1 antibody|HSXIAPAF1 antibody|XAF 1 antibody|XAF1 antibody|XAF1_HUMAN antibody|XIAP associated factor 1 antibody|XIAP-associated factor 1 antibody|XIAPAF1 antibody
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