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PIM1 抗体 (C-Term)

Name: PIM1 抗体 (C-Term)
SKU: ABIN3043606
Availability: OutOfStock

This anti-PIM1 antibody is a 兔多克隆 antibody detecting PIM1 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Anti- PIM1Picoband antibody, Western blotting All lanes: Anti PIM1 at 0. (PIM1 抗体 (C-Term))

1 image

(1 reference)

产品编号 ABIN3043606

发货至: 中国

Quick Overview for PIM1 抗体 (C-Term) (ABIN3043606)

抗原

See all PIM1 抗体

PIM1 (Pim-1 Oncogene (PIM1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PIM1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PIM1 Primary Antibody

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AA 373-404, C-Term

原理

Anti-PIM1 Antibody Picoband®

序列

EEIQNHPWMQ DVLLPQETAE IHLHSLSPGP SK

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-PIM1 Antibody Picoband® (ABIN3043606). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human PIM1, different from the related mouse sequence by seven amino acids and from the related rat sequence by two amino acids.

亚型

IgG
anti-Pim-1 Oncogene (PIM1) (AA 122-261) antibody
PIM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 1-100) antibody
PIM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C10 unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 1-313) antibody
PIM1 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 1-100) antibody
PIM1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2C9 unconjugated

anti-Pim-1 Oncogene (PIM1) (Internal Region) antibody
PIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 129-268) antibody
PIM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 25-86) antibody
PIM1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 1-314) antibody
PIM1 适用: 人 ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 6A2 unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 1-314) antibody
PIM1 适用: 人 ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Pim-1 Oncogene (PIM1) (AA 1-313) antibody
PIM1 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 6A2 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Amson, R., Sigaux, F., Przedborski, S., Flandrin, G., Givol, D., Telerman, A. The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias. Proc. Nat. Acad. Sci. 86: 8857-8861, 1989. 2. Bachmann M, Möröy T (April 2005). "The serine/threonine kinase Pim-1". Int. J. Biochem. Cell Biol. 37 (4): 726-30. 3. Muraski, J. A., Rota, M., Misao, Y., Fransioli, J., Cottage, C., Gude, N., Esposito, G., Delucchi, F., Arcarese, M., Alvarez, R., Siddiqi, S., Emmanuel, G. N., and 13 others. Pim-1 regulates cardiomyocyte survival downstream of Akt. Nature Med. 13: 1467-1475, 2007. Note: Erratum: Nature Med. 14: 350 only, 2008.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Wu, Lu, He, Jin: "PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population." in: OncoTargets and therapy, Vol. 9, pp. 2919-25, (2016) (PubMed).
抗原

PIM1 (Pim-1 Oncogene (PIM1))

别名

PIM1

背景

Synonyms: Serine/threonine-protein kinase pim-1,2.7.11.1,PIM1,
Tissue Specificity: Expressed primarily in cells of the hematopoietic and germline lineages. Isoform 1 and isoform 2 are both expressed in prostate cancer cell lines. .
Background: Proto-oncogene serine/threonine-protein kinase Pim-1 is an enzyme that in humans is encoded by the PIM1 gene. It is mapped to 6p21.2. Primarily expressed in spleen, thymus, bone marrow, prostate, oral epithelial, hippocampus and fetal liver cells, Pim-1 has also been found to be highly expressed in cell cultures isolated from human tumors. Pim-1 is mainly involved in cell cycle progression, apoptosis and transcriptional activation, as well as more general signal transduction pathways. It has been found a physiologic role of the PIM1 oncogene during hematopoietic development and a deregulation of the gene in various leukemias. PIM1 also has a role in cardioprotection downstream of AKT activation.
Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.

分子量

44 kDa

基因ID

5292

UniProt

P11309

途径

Glycosaminoglycan Metabolic Process