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Parvin alpha 抗体 (Middle Region)

This anti-Parvin alpha antibody is a 兔 多克隆 antibody detecting Parvin alpha in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3043590
发货至: 中国

Quick Overview for Parvin alpha 抗体 (Middle Region) (ABIN3043590)

抗原

See all Parvin alpha (PARVA) 抗体
Parvin alpha (PARVA) (Parvin, alpha (PARVA))

适用

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人, 小鼠, 大鼠

宿主

  • 47
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  • 1

克隆类型

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多克隆

标记

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This Parvin alpha antibody is un-conjugated

应用范围

  • 48
  • 26
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
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    AA 155-185, Middle Region

    原理

    Anti-Parvin alpha/PARVA Antibody Picoband®

    序列

    QKLQTVLEKI NETLKLPPRS IKWNVDSVHA K

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Parvin alpha/PARVA Antibody Picoband® (ABIN3043590). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Parvin alpha, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: PARVA parvin, alpha". 2. Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci 114 (Pt 3): 525-38. 3. Zhang Y, Chen K, Tu Y, Wu C (2004). "Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival.". J. Biol. Chem. 279 (40): 41695-705.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Parvin alpha (PARVA) (Parvin, alpha (PARVA))

    别名

    PARVA

    背景

    Synonyms: Alpha-parvin,Actopaxin,CH-ILKBP,Calponin-like integrin-linked kinase-binding protein,Matrix-remodeling-associated protein 2,PARVA,MXRA2,

    Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. .

    Background: Parvin alpha is a protein that in humans is encoded by the PARVA gene. It is located on 11p15.3. PARVA belongs to the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.

    Sequence Similarities: Belongs to the parvin family.

    分子量

    42 kDa

    基因ID

    55742

    途径

    Smooth Muscle Cell Migration
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