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Occludin 抗体 (AA 373-522)

This anti-Occludin antibody is a 兔多克隆 antibody detecting Occludin in WB 和 IHC. Suitable for 人.

Western Blotting (WB) image for anti-Occludin (OCLN) (AA 373-522) antibody (ABIN3043585) (Occludin 抗体 (AA 373-522))

Anti- Occludin antibody,IHC(P) IHC(P): Human Mammary Cancer Tissue (Occludin 抗体 (AA 373-522))

2 images

产品编号 ABIN3043585

发货至: 中国

Quick Overview for Occludin 抗体 (AA 373-522) (ABIN3043585)

抗原

See all Occludin (OCLN) 抗体

Occludin (OCLN)

适用

126
64
44
34
18
12
4
3
3
2
2
2

人

宿主

兔

克隆类型

多克隆

标记

63
11
6
5
3
3
2
2
2
2
2
2
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2
2
2
2
2
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1

This Occludin antibody is un-conjugated

应用范围

105
46
37
32
26
26
20
20
17
15
13
6
2
2
1
1

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product OCLN Primary Antibody

抗原表位
23

16

16

11

9

6

6

3

3

3

2

2

2

2

1

1

1

1

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1

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1
AA 373-522

原理

Anti-Occludin/OCLN Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Occludin/OCLN Antibody (ABIN3043585). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Occludin recombinant protein (Position: N373-T522). Human Occludin shares 89% amino acid (aa) sequence identity with both mouse and rat Occludin.

亚型

IgG
anti-Occludin (OCLN) (AA 431-522) antibody
OCLN 适用: 人, 小鼠, Pig WB, ELISA, FACS, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Occludin (OCLN) (AA 263-522) antibody
OCLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Occludin (OCLN) (C-Term) antibody
OCLN 适用: 人 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

anti-Occludin (OCLN) (AA 423-522) antibody
OCLN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Occludin (OCLN) (AA 1-522) antibody
OCLN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Occludin (OCLN) (AA 1-522) antibody
OCLN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Occludin (OCLN) (AA 282-415) antibody
OCLN 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal OCLN-2181 unconjugated

anti-Occludin (OCLN) (AA 285-430) antibody
OCLN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Occludin (OCLN) (C-Term) antibody
OCLN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal OC-3F10 unconjugated

anti-Occludin (OCLN) (AA 282-415) antibody
OCLN 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-415M unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Ando-Akatsuka, Y., Saitou, M., Hirase, T., Kishi, M., Sakakibara, A., Itoh, M., Yonemura, S., Furuse, M., Tsukita, S. Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J. Cell Biol. 133: 43-47, 1996. 2. Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., Shinjo, F., Liu, Y., Dembowy, J., Taylor, I. W., Luga, V., Przulj, N., Robinson, M., Suzuki, H., Hayashizaki, Y., Jurisica, I., Wrana, J. L. High-throughput mapping of a dynamic signaling network in mammalian cells. Science 307: 1621-1625, 2005. 3. Du, D., Xu, F., Yu, L., Zhang, C., Lu, X., Yuan, H., Huang, Q., Zhang, F., Bao, H., Jia, L., Wu, X., Zhu, X., Zhang, X., Zhang, Z., Chen, Z. The tight junction protein, occludin, regulates the ional migration of epithelial cells. Dev. Cell 18: 52-63, 2010.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

Occludin (OCLN)

别名

OCLN

背景

Synonyms: Occludin,OCLN,
Tissue Specificity: Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.
Background: Occludin is an integral membrane protein that is located at tight junctions. It is a member of a family of proteins containing the highly conserved Marvel domain, which contains 4 transmembrane-helix regions. This gene is mapped to 5q13.2. Occludin regulates TGF-beta receptor type I localization for efficient TGF-beta-dependent dissolution of tight junctions during epithelial-mesenchymal transitions. Human Occludin is an essential hepatitis C virus (HCV) cell entry factor that is able to render murine cells infectable with HCV glycoproteins. It has been found that occludin is involved in cell migration and functions to recruit active PI3 kinase to the leading edge, resulting in RAC1 activation and formation of lamellipodia.
Sequence Similarities: Belongs to the ELL/occludin family.

分子量

59 kDa

基因ID

100506658

UniProt

Q16625

途径

Cell-Cell Junction Organization, Hepatitis C

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