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NME1 抗体 (N-Term)

Name: NME1 抗体 (N-Term)
SKU: ABIN3043572
Availability: OutOfStock

Cited in 1 publication. The 兔多克隆 anti-NME1 antibody (ABIN3043572) specifically detects NME1 in WB 和 FACS. The antibody is reactive with 人, 小鼠和大鼠 samples.

Western Blotting (WB) image for anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibody (ABIN3043572) (NME1 抗体 (N-Term))

Flow Cytometry analysis of HEL cells using anti-NM23A/NME1 antibody (ABIN3043572). (NME1 抗体 (N-Term))

FACS

Western blot analysis of NM23A/NME1 using anti-NM23A/NME1 antibody (ABIN3043572). (NME1 抗体 (N-Term))

4 images

(1 reference)

产品编号 ABIN3043572

发货至: 中国

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Quick Overview for NME1 抗体 (N-Term) (ABIN3043572)

抗原

See all NME1 抗体

NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This NME1 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS)

Discover our top product NME1 Primary Antibody

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N-Term

原理

Anti-NM23A/NME1 Antibody

序列

KRFEQKGFRL VGLKFMQASE DLLKEHYVDL KDR

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

different from the related mouse,rat sequences by two amino acids.

产品特性

Anti-NM23A/NME1 Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human NM23A, different from the related mouse and rat sequences by two amino acids.

亚型

IgG
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 43-152) antibody
NME1 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) antibody
NME1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2H1 unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody
NME1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H2 unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody
KD Validated NME1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2195 unconjugated Recombinant Antibody

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody
NME1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4B2 unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 6-147) antibody
NME1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibody
NME1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠 WB, IHC, DB 宿主: 兔 Polyclonal unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibody
NME1 适用: 人, 小鼠, 大鼠, 犬, 猴, Pig, Cow, 马, 兔, 小鸡, 非洲爪蟾, 斑马鱼, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (C-Term) antibody
NME1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 25-54), (N-Term) antibody
NME1 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB03726 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Jin, Dai: "Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma." in: Molecular and clinical oncology, Vol. 5, Issue 1, pp. 107-110, (2016) (PubMed).
抗原

NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

别名

NME1

背景

Background: NME1 (NME/NM23 nucleoside diphosphate kinase 1), also called non-metastatic cells 1, protein (NM23A) expressed in, NM23, NM23-H1, NDPKA, GAAD or AWD, is an enzyme that in humans is encoded by the NME1 gene. The promoters of the mouse and human NME1 genes, like those of other NME genes, contain several binding sites for AP2, NF1, Sp1, LEF1, and response elements to glucocorticoid receptors. The NME1 gene is mapped on 17q21.33. Immunofluorescence microscopy demonstrated colocalization of NME1 in nuclei of B cells expressing EBNA3C. Expression of EBNA3C reversed the ability of NME1 to inhibit migration of BL and breast carcinoma cells. NM23H1 bound SET and was released from inhibition by GZMA cleavage of SET. After GZMA loading or cytotoxic T lymphocyte attack, SET and NM23H1 translocated to the nucleus and SET was degraded, allowing NM23H1 to nick chromosomal DNA. Using a Drosophila model system, Dammai et al. (2003) showed that the Drosophila NME1 homolog, awd, regulates trachea cell motility by modulating FGFR levels through a dynamin -mediated pathway.
Gene Full Name: NME/NM23 nucleoside diphosphate kinase 1

分子量

17 kDa

基因ID

4830

UniProt

P15531

途径

Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process