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- 抗原 See all PSCA 抗体
- PSCA (Prostate Stem Cell Antigen (PSCA))
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抗原表位
- AA 21-95
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSCA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Prostate stem cell antigen(PSCA) detection. Tested with WB in Human,Mouse,Rat.
- 交叉反应 (详细)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Prostate stem cell antigen(PSCA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: prostate stem cell antigen
Protein Name: Prostate stem cell antigen - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human PSCA recombinant protein (Position: L21-S95). Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.
- 亚型
- IgG
- Top Product
- Discover our top product PSCA Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for PSCA is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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PSCA rs2294008 polymorphism contributes to the decreased risk for cervical cancer in a Chinese population." in: Scientific reports, Vol. 6, pp. 23465, (2017) (PubMed).
: "Small interference RNA-mediated silencing of prostate stem cell antigen attenuates growth, reduces migration and invasion of human prostate cancer PC-3M cells." in: Urologic oncology, Vol. 31, Issue 3, pp. 343-51, (2013) (PubMed).
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PSCA rs2294008 polymorphism contributes to the decreased risk for cervical cancer in a Chinese population." in: Scientific reports, Vol. 6, pp. 23465, (2017) (PubMed).
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- 抗原
- PSCA (Prostate Stem Cell Antigen (PSCA))
- 别名
- PSCA (PSCA 产品)
- 背景
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PSCA is also known as PRO232. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
Synonyms: PRO 232 antibody|PRO232 antibody|Prostate stem cell antigen antibody - 基因ID
- 8000
- UniProt
- O43653
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