PON2 抗体 (C-Term)
Quick Overview for PON2 抗体 (C-Term) (ABIN3043546)
抗原
See all PON2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-273, C-Term
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原理
- Anti-PON2 Antibody Picoband®
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序列
- AHEIHVLEKH TNMNLTQLKV LELDTLVDNL SID
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PON2 Antibody Picoband® (ABIN3043546). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PON2, different from the related mouse and rat sequences by four amino acids.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: PON2 paraoxonase 2" 2. Mochizuki H, Scherer SW, Xi T, Nickle DC, Majer M, Huizenga JJ, Tsui LC, Prochazka M (Aug 1998). "Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence". Gene 213 (1-2): 149-57. 3. Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN (Sep 1996). "The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family". Genomics 33 (3): 498-507. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PON2 (Paraoxonase 2 (PON2))
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别名
- PON2
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背景
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Synonyms: Serum paraoxonase/arylesterase 2,PON 2,3.1.1.2,3.1.1.81,Aromatic esterase 2,A-esterase 2,Serum aryldialkylphosphatase 2,PON2,
Tissue Specificity: Widely expressed with highest expression in liver, lung, placenta, testis and heart. .
Background: PON2 is an enzyme that in humans is encoded by the PON2 gene. It is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.
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分子量
- 39 kDa
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基因ID
- 5445
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UniProt
- Q15165
抗原
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