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PON2 抗体

PON2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855759
发货至: 中国
  • 抗原 See all PON2 抗体
    PON2 (Paraoxonase 2 (PON2))
    适用
    • 62
    • 25
    • 17
    宿主
    • 57
    • 3
    • 2
    • 1
    克隆类型
    • 53
    • 10
    多克隆
    标记
    • 25
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PON2 antibody is un-conjugated
    应用范围
    • 43
    • 34
    • 33
    • 14
    • 14
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to PON2 (paraoxonase 2)
    PON2 antibody [N1C2]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PON2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PON2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: A431 , Mouse liver

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Devarajan, Su, Grijalva, Yalamanchi, Yalamanchi, Gao, Trost, Nwokedi, Farias-Eisner, Farias-Eisner, Fogelman, Reddy: "Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer." in: Cell death & disease, Vol. 9, Issue 3, pp. 392, (2019) (PubMed).

  • 抗原
    PON2 (Paraoxonase 2 (PON2))
    别名
    paraoxonase 2 (PON2 产品)
    别名
    PON2 antibody, pon1 antibody, MGC53915 antibody, pon2 antibody, 6330405I24Rik antibody, AI481612 antibody, serum paraoxonase/arylesterase 2 antibody, paraoxonase 2 antibody, paraoxonase 2 L homeolog antibody, Serum paraoxonase/arylesterase 2 antibody, LOC100303695 antibody, PON2 antibody, pon2.L antibody, BDBG_00600 antibody, pon2 antibody, Pon2 antibody
    背景
    This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

    Cellular Localization: Membrane, Peripheral membrane protein
    分子量
    39 kDa
    基因ID
    5445
    UniProt
    Q15165
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