TREX1 抗体 (Middle Region)
Quick Overview for TREX1 抗体 (Middle Region) (ABIN3043537)
抗原
See all TREX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 156-185, Middle Region
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原理
- Anti-TREX1 Antibody Picoband®
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序列
- DDNLANLLLA FLRRQPQPWC LVAHNGDRYD
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TREX1 Antibody Picoband® (ABIN3043537). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TREX1, different from the related mouse sequence by four amino acids.
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亚型
- IgG
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anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-369) antibody
TREX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-270) antibodyTREX1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-270) antibodyTREX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-304) antibodyTREX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-100) antibodyTREX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 6-369) antibodyTREX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-304) antibodyTREX1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-100) antibodyTREX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) (AA 1-369) antibodyTREX1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 1 (TREX1) antibodyTREX1 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: TREX1 three prime repair exonuclease 1". 2. Mazur DJ, Perrino FW (Aug 1999). "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases". J Biol Chem 274 (28): 19655-60. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TREX1 (three Prime Repair Exonuclease 1 (TREX1))
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别名
- TREX1
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背景
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Synonyms: Three-prime repair exonuclease 1,3.1.11.2,3'-5' exonuclease TREX1,DNase III,TREX1,
Tissue Specificity: Detected in thymus, spleen, liver, brain, heart, small intestine and colon. .
Background: Three prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.
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分子量
- 33 kDa
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基因ID
- 11277
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途径
- Apoptosis
抗原
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