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TREX1 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects TREX1 in WB. It exhibits reactivity toward 人.
产品编号 ABIN3043537
发货至: 中国
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Quick Overview for TREX1 抗体 (Middle Region) (ABIN3043537)

抗原

See all TREX1 抗体
TREX1 (three Prime Repair Exonuclease 1 (TREX1))

适用

  • 49
  • 6
  • 5

宿主

  • 43
  • 7

克隆类型

  • 27
  • 23
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
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  • 1
This TREX1 antibody is un-conjugated

应用范围

  • 34
  • 18
  • 17
  • 13
  • 10
  • 6
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-185, Middle Region

    原理

    Anti-TREX1 Antibody

    序列

    DDNLANLLLA FLRRQPQPWC LVAHNGDRYD

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TREX1 Antibody (ABIN3043537). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human TREX1, different from the related mouse sequence by four amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    TREX1 (three Prime Repair Exonuclease 1 (TREX1))

    别名

    TREX1

    背景

    Synonyms: Three-prime repair exonuclease 1,3.1.11.2,3'-5' exonuclease TREX1,DNase III,TREX1,

    Tissue Specificity: Detected in thymus, spleen, liver, brain, heart, small intestine and colon. .

    Background: Three prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.

    分子量

    33 kDa

    基因ID

    11277

    途径

    Apoptosis
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