TRAP1 抗体 (AA 571-704)
Quick Overview for TRAP1 抗体 (AA 571-704) (ABIN3043536)
抗原
See all TRAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 571-704
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原理
- Anti-TRAP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-TRAP1 Antibody Picoband® (ABIN3043536). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TRAP1 recombinant protein (Position: A571-H704). Human TRAP1 shares 91.7% and 94% amino acid (aa) sequence identity with mouse and rat TRAP1, respectively.
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亚型
- IgG
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anti-TNF Receptor-Associated Protein 1 (TRAP1) antibody
TRAP1 适用: 人, 大鼠, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) (AA 1-704) antibodyTRAP1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) antibodyTRAP1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) (AA 445-704) antibodyTRAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) antibodyKO Validated TRAP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) antibodyTRAP1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) (AA 60-308) antibodyTRAP1 适用: 人 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) (Internal Region) antibodyTRAP1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) antibodyTRAP1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Protein 1 (TRAP1) (AA 1-704) antibodyTRAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: TRAP1 TNF receptor-associated protein 1". 2. Felts SJ, Owen BA, Nguyen P, Trepel J, Donner DB, Toft DO (March 2000). "The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties". J Biol Chem 275 (5): 3305-12. 3. Song HY, Dunbar JD, Zhang YX, Guo D, Donner DB (March 1995). "Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor". J Biol Chem 270 (8): 3574-81. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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别名
- TRAP1
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背景
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Synonyms: Heat shock protein 75 kDa, mitochondrial,HSP 75,TNFR-associated protein 1,Tumor necrosis factor type 1 receptor-associated protein,TRAP-1,TRAP1,HSP75,
Tissue Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is higly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors. .
Background: Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.
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分子量
- 80 kDa
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基因ID
- 10131
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UniProt
- Q12931
抗原
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